SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)
5jbg LGP2
(Gallus
gallus)
3 / 3 ALA A 572
VAL A 570
TRP A 602
None
0.99A 1gmkC-5jbgA:
undetectable
1gmkD-5jbgA:
undetectable
1gmkC-5jbgA:
2.18
1gmkD-5jbgA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 480
ILE A 293
THR A 296
GLN A 376
None
1.30A 1kglA-5jbgA:
undetectable
1kglA-5jbgA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)
5jbg LGP2
(Gallus
gallus)
5 / 12 GLY A 368
ALA A 472
LEU A 443
ASN A 431
PHE A 425
None
1.18A 1nw3A-5jbgA:
2.2
1nw3A-5jbgA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)
5jbg LGP2
(Gallus
gallus)
3 / 3 ASP A 420
THR A 423
GLU A  65
None
0.81A 1pj7A-5jbgA:
undetectable
1pj7A-5jbgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)
5jbg LGP2
(Gallus
gallus)
3 / 3 ARG A 453
TYR A 477
LYS A 216
None
1.07A 1uujB-5jbgA:
1.4
1uujB-5jbgA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.70A 1v54C-5jbgA:
2.0
1v54J-5jbgA:
undetectable
1v54C-5jbgA:
15.81
1v54J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.83A 1v54C-5jbgA:
2.0
1v54J-5jbgA:
undetectable
1v54C-5jbgA:
15.81
1v54J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.69A 1v54P-5jbgA:
3.1
1v54W-5jbgA:
undetectable
1v54P-5jbgA:
15.81
1v54W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.81A 1v54P-5jbgA:
3.1
1v54W-5jbgA:
undetectable
1v54P-5jbgA:
15.81
1v54W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
5jbg LGP2
(Gallus
gallus)
5 / 11 VAL A 370
ILE A 355
ILE A 396
LEU A 432
PHE A 360
None
1.04A 1z11B-5jbgA:
undetectable
1z11B-5jbgA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
5jbg LGP2
(Gallus
gallus)
5 / 10 VAL A 370
ILE A 355
ILE A 396
LEU A 432
PHE A 360
None
1.09A 1z11C-5jbgA:
undetectable
1z11C-5jbgA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
5jbg LGP2
(Gallus
gallus)
5 / 10 VAL A 370
ILE A 355
ILE A 396
LEU A 432
PHE A 360
None
1.10A 1z11D-5jbgA:
undetectable
1z11D-5jbgA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.71A 2dyrC-5jbgA:
3.1
2dyrJ-5jbgA:
undetectable
2dyrC-5jbgA:
15.81
2dyrJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.83A 2dyrC-5jbgA:
3.1
2dyrJ-5jbgA:
undetectable
2dyrC-5jbgA:
15.81
2dyrJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.68A 2dyrP-5jbgA:
3.0
2dyrW-5jbgA:
undetectable
2dyrP-5jbgA:
15.81
2dyrW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.85A 2dyrP-5jbgA:
3.0
2dyrW-5jbgA:
undetectable
2dyrP-5jbgA:
15.81
2dyrW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.73A 2eikC-5jbgA:
3.1
2eikJ-5jbgA:
undetectable
2eikC-5jbgA:
15.81
2eikJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.85A 2eikC-5jbgA:
3.1
2eikJ-5jbgA:
undetectable
2eikC-5jbgA:
15.81
2eikJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.66A 2eikP-5jbgA:
3.1
2eikW-5jbgA:
undetectable
2eikP-5jbgA:
15.81
2eikW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.80A 2eikP-5jbgA:
3.1
2eikW-5jbgA:
undetectable
2eikP-5jbgA:
15.81
2eikW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.70A 2eilC-5jbgA:
3.1
2eilJ-5jbgA:
undetectable
2eilC-5jbgA:
15.81
2eilJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.81A 2eilC-5jbgA:
3.1
2eilJ-5jbgA:
undetectable
2eilC-5jbgA:
15.81
2eilJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.87A 2eimP-5jbgA:
3.1
2eimW-5jbgA:
undetectable
2eimP-5jbgA:
15.81
2eimW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)
5jbg LGP2
(Gallus
gallus)
5 / 12 ILE A 445
CYH A 448
VAL A 451
PHE A 425
LEU A 401
None
1.02A 2ft9A-5jbgA:
undetectable
2ft9A-5jbgA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5jbg LGP2
(Gallus
gallus)
4 / 8 TYR A 287
GLN A 241
MET A 244
ILE A 240
None
1.11A 2xytE-5jbgA:
undetectable
2xytE-5jbgA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5jbg LGP2
(Gallus
gallus)
4 / 8 TYR A 287
GLN A 241
MET A 244
ILE A 240
None
1.13A 2xytH-5jbgA:
undetectable
2xytH-5jbgA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 6 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.88A 3abkP-5jbgA:
3.1
3abkW-5jbgA:
undetectable
3abkP-5jbgA:
15.81
3abkW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.64A 3ag2C-5jbgA:
3.1
3ag2C-5jbgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.65A 3ag2P-5jbgA:
undetectable
3ag2W-5jbgA:
undetectable
3ag2P-5jbgA:
15.81
3ag2W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.86A 3ag2P-5jbgA:
undetectable
3ag2W-5jbgA:
undetectable
3ag2P-5jbgA:
15.81
3ag2W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.65A 3ag4C-5jbgA:
3.1
3ag4J-5jbgA:
undetectable
3ag4C-5jbgA:
15.81
3ag4J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 8 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.83A 3ag4C-5jbgA:
3.1
3ag4J-5jbgA:
undetectable
3ag4C-5jbgA:
15.81
3ag4J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.65A 3ag4P-5jbgA:
3.1
3ag4W-5jbgA:
undetectable
3ag4P-5jbgA:
15.81
3ag4W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.84A 3ag4P-5jbgA:
3.1
3ag4W-5jbgA:
undetectable
3ag4P-5jbgA:
15.81
3ag4W-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.71A 3asnC-5jbgA:
3.1
3asnJ-5jbgA:
undetectable
3asnC-5jbgA:
15.81
3asnJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.91A 3asnC-5jbgA:
3.1
3asnJ-5jbgA:
undetectable
3asnC-5jbgA:
15.81
3asnJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.84A 3asnP-5jbgA:
2.0
3asnW-5jbgA:
undetectable
3asnP-5jbgA:
15.81
3asnW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.83A 3asoP-5jbgA:
2.0
3asoW-5jbgA:
undetectable
3asoP-5jbgA:
15.81
3asoW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5jbg LGP2
(Gallus
gallus)
5 / 12 ILE A 450
ALA A 398
ILE A 396
VAL A 370
PHE A 360
None
1.12A 3b2rA-5jbgA:
undetectable
3b2rA-5jbgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5jbg LGP2
(Gallus
gallus)
5 / 11 ILE A 450
ALA A 398
ILE A 396
VAL A 370
PHE A 360
None
1.14A 3b2rB-5jbgA:
undetectable
3b2rB-5jbgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5jbg LGP2
(Gallus
gallus)
4 / 4 GLN A 357
GLN A 394
GLY A 393
HIS A 395
None
1.43A 3huoA-5jbgA:
undetectable
3huoA-5jbgA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)
5jbg LGP2
(Gallus
gallus)
5 / 12 ASN A 191
ILE A  21
THR A 167
ILE A 505
ILE A 185
None
1.05A 3kpbA-5jbgA:
undetectable
3kpbA-5jbgA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)
5jbg LGP2
(Gallus
gallus)
4 / 5 LEU A 349
LEU A 352
LEU A 385
SER A 383
None
1.03A 3vhuA-5jbgA:
undetectable
3vhuA-5jbgA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 6 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.82A 3wg7C-5jbgA:
3.1
3wg7J-5jbgA:
undetectable
3wg7C-5jbgA:
15.81
3wg7J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.48A 3x2qC-5jbgA:
3.1
3x2qJ-5jbgA:
undetectable
3x2qC-5jbgA:
15.81
3x2qJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.85A 3x2qC-5jbgA:
3.1
3x2qJ-5jbgA:
undetectable
3x2qC-5jbgA:
15.81
3x2qJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.45A 3x2qP-5jbgA:
3.1
3x2qW-5jbgA:
undetectable
3x2qP-5jbgA:
15.81
3x2qW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.84A 3x2qP-5jbgA:
3.1
3x2qW-5jbgA:
undetectable
3x2qP-5jbgA:
15.81
3x2qW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)
5jbg LGP2
(Gallus
gallus)
5 / 11 ILE A 236
HIS A 283
LEU A 284
LEU A 324
LEU A 306
None
1.06A 4p65E-5jbgA:
undetectable
4p65F-5jbgA:
undetectable
4p65J-5jbgA:
undetectable
4p65L-5jbgA:
undetectable
4p65E-5jbgA:
2.84
4p65F-5jbgA:
4.00
4p65J-5jbgA:
4.00
4p65L-5jbgA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)
5jbg LGP2
(Gallus
gallus)
5 / 12 LEU A 324
LEU A 306
ILE A 236
HIS A 283
LEU A 284
None
0.98A 4p65B-5jbgA:
undetectable
4p65D-5jbgA:
undetectable
4p65I-5jbgA:
undetectable
4p65J-5jbgA:
undetectable
4p65B-5jbgA:
4.00
4p65D-5jbgA:
4.00
4p65I-5jbgA:
2.84
4p65J-5jbgA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)
5jbg LGP2
(Gallus
gallus)
5 / 12 LEU A 306
LEU A 324
ILE A 236
HIS A 283
LEU A 284
None
0.97A 4p65F-5jbgA:
undetectable
4p65H-5jbgA:
undetectable
4p65K-5jbgA:
undetectable
4p65L-5jbgA:
undetectable
4p65F-5jbgA:
4.00
4p65H-5jbgA:
4.00
4p65K-5jbgA:
2.84
4p65L-5jbgA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5jbg LGP2
(Gallus
gallus)
4 / 6 GLY A 618
PHE A 636
ILE A 633
PHE A 552
None
1.09A 4qogA-5jbgA:
undetectable
4qogB-5jbgA:
undetectable
4qogA-5jbgA:
15.09
4qogB-5jbgA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
5jbg LGP2
(Gallus
gallus)
4 / 5 PRO A 641
HIS A 553
TYR A 647
VAL A 653
None
1.31A 4s0vA-5jbgA:
undetectable
4s0vA-5jbgA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.65A 5b1bP-5jbgA:
3.1
5b1bW-5jbgA:
undetectable
5b1bP-5jbgA:
15.81
5b1bW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
1.00A 5b1bP-5jbgA:
3.1
5b1bW-5jbgA:
undetectable
5b1bP-5jbgA:
15.81
5b1bW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
5jbg LGP2
(Gallus
gallus)
5 / 12 GLU A 175
GLY A 173
GLU A 441
CYH A 133
THR A 167
None
0.73A 5fhzD-5jbgA:
undetectable
5fhzD-5jbgA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)
5jbg LGP2
(Gallus
gallus)
3 / 3 THR A 372
SER A 377
ASP A 295
None
0.70A 5kvaB-5jbgA:
3.5
5kvaB-5jbgA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
5jbg LGP2
(Gallus
gallus)
3 / 3 HIS A 574
GLU A 571
TRP A 602
G  X   2 ( 3.8A)
C  X  24 ( 4.2A)
None
1.11A 5odiD-5jbgA:
undetectable
5odiD-5jbgA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
5jbg LGP2
(Gallus
gallus)
3 / 3 HIS A 574
GLU A 571
TRP A 602
G  X   2 ( 3.8A)
C  X  24 ( 4.2A)
None
0.98A 5odqD-5jbgA:
undetectable
5odqD-5jbgA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
5jbg LGP2
(Gallus
gallus)
3 / 3 HIS A 574
GLU A 571
TRP A 602
G  X   2 ( 3.8A)
C  X  24 ( 4.2A)
None
1.12A 5odrD-5jbgA:
undetectable
5odrD-5jbgA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 5 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.96A 5x19C-5jbgA:
3.1
5x19J-5jbgA:
undetectable
5x19C-5jbgA:
15.81
5x19J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 385
PHE A 434
LEU A 432
PHE A 360
None
0.94A 5x1fP-5jbgA:
2.0
5x1fW-5jbgA:
undetectable
5x1fP-5jbgA:
15.81
5x1fW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)
5jbg LGP2
(Gallus
gallus)
5 / 12 CYH A 102
LEU A  53
ALA A  51
ALA A 110
ILE A 106
None
None
None
None
C  X  24 ( 4.4A)
1.00A 5xiwB-5jbgA:
undetectable
5xiwB-5jbgA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.55A 5z85C-5jbgA:
3.1
5z85J-5jbgA:
undetectable
5z85C-5jbgA:
15.81
5z85J-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.51A 5zcoC-5jbgA:
2.0
5zcoJ-5jbgA:
undetectable
5zcoC-5jbgA:
15.81
5zcoJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.51A 5zcqC-5jbgA:
2.0
5zcqJ-5jbgA:
undetectable
5zcqC-5jbgA:
15.81
5zcqJ-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jbg LGP2
(Gallus
gallus)
4 / 7 LEU A 335
GLN A 336
PHE A 229
LEU A 233
None
0.52A 5zcqP-5jbgA:
3.1
5zcqW-5jbgA:
undetectable
5zcqP-5jbgA:
15.81
5zcqW-5jbgA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CCV_C_RFPC1205_1
(-)
5jbg LGP2
(Gallus
gallus)
5 / 12 GLN A 418
SER A 435
LEU A 401
ILE A 369
HIS A 134
U  X  22 ( 4.4A)
None
None
None
None
1.42A 6ccvC-5jbgA:
undetectable
6ccvC-5jbgA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
5jbg LGP2
(Gallus
gallus)
4 / 7 HIS A  69
ARG A  39
HIS A  36
ASP A  73
None
1.30A 6mn4F-5jbgA:
undetectable
6mn4F-5jbgA:
17.81