SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1498_1 (CYTOCHROME P450 3A4)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	5 / 11	ILE H 111 PHE H 108 ALA H 107 ARG H 163 LEU H 67	None None None U 21336 ( 4.4A) None	1.19A	2v0mD-5jbhH: undetectable	2v0mD-5jbhH: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM7_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	5jbh	30S RIBOSOMAL PROTEIN ES24 (Pyrococcus abyssi)	4 / 7	TYR V 59 ILE V 23 ILE V 64 HIS V 25	U 2 572 ( 4.5A) None None None	1.05A	2zm7A-5jbhV: undetectable	2zm7A-5jbhV: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_A_RITA600_1 (CYTOCHROME P450 3A4)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	5 / 12	ILE H 111 PHE H 108 ALA H 107 ILE H 71 ALA H 166	None	1.02A	3nxuA-5jbhH: undetectable	3nxuA-5jbhH: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	5 / 12	ILE H 111 PHE H 108 ALA H 107 ILE H 71 ALA H 166	None	1.03A	3nxuB-5jbhH: undetectable	3nxuB-5jbhH: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K7A_A_MXDA1002_1 (ANDROGEN RECEPTOR)	5jbh	30S RIBOSOMAL PROTEIN ES27 (Pyrococcus abyssi)	3 / 3	GLU Y 47 TRP Y 38 LYS Y 42	None None G 2 986 ( 4.6A)	1.39A	4k7aA-5jbhY: undetectable	4k7aA-5jbhY: 10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K7A_A_MXDA1002_1 (ANDROGEN RECEPTOR)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	3 / 3	GLU H 128 TRP H 125 LYS H 34	None	1.04A	4k7aA-5jbhH: undetectable	4k7aA-5jbhH: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_1 (NEURAMINIDASE)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	3 / 3	ARG H 157 ASP H 30 ARG H 133	None	0.92A	4mx0A-5jbhH: undetectable	4mx0A-5jbhH: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JMN_A_FUAA1101_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	4 / 5	ILE H 188 LYS H 70 ILE H 71 VAL H 104	None U 21336 ( 4.1A) None None	0.80A	5jmnA-5jbhH: undetectable	5jmnA-5jbhH: 11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V02_R_657R201_0 (CALMODULIN-1 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	5 / 10	ALA H 126 LEU H 123 VAL H 122 LEU H 67 GLU H 187	None	1.08A	5v02B-5jbhH: undetectable 5v02R-5jbhH: undetectable	5v02B-5jbhH: 21.40 5v02R-5jbhH: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC0_A_RITA602_1 (CYTOCHROME P450 3A4)	5jbh	30S RIBOSOMAL PROTEIN US7 (Pyrococcus abyssi)	5 / 12	ILE H 111 PHE H 108 ALA H 107 ILE H 71 ALA H 166	None	1.03A	5vc0A-5jbhH: undetectable	5vc0A-5jbhH: 18.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2V0M_D_KLND1498_1","CYTOCHROME P450 3A4","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",5,"ILE H 111;PHE H 108;ALA H 107;ARG H 163;LEU H  67","None;None;None;  U 21336 ( 4.4A);None","1.19A","2v0mD-5jbhH:undetectable","2v0mD-5jbhH:18.67"],["2ZM7_A_ACAA501_1","6-AMINOHEXANOATE-DIMER HYDROLASE","5jbh","30S RIBOSOMAL PROTEIN ES24","Pyrococcus abyssi",4,"TYR V  59;ILE V  23;ILE V  64;HIS V  25","  U 2 572 ( 4.5A);None;None;None","1.05A","2zm7A-5jbhV:undetectable","2zm7A-5jbhV:12.07"],["3NXU_A_RITA600_1","CYTOCHROME P450 3A4","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",5,"ILE H 111;PHE H 108;ALA H 107;ILE H  71;ALA H 166","None","1.02A","3nxuA-5jbhH:undetectable","3nxuA-5jbhH:18.67"],["3NXU_B_RITB600_1","CYTOCHROME P450 3A4","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",5,"ILE H 111;PHE H 108;ALA H 107;ILE H  71;ALA H 166","None","1.03A","3nxuB-5jbhH:undetectable","3nxuB-5jbhH:18.67"],["4K7A_A_MXDA1002_1","ANDROGEN RECEPTOR","5jbh","30S RIBOSOMAL PROTEIN ES27","Pyrococcus abyssi",3,"GLU Y  47;TRP Y  38;LYS Y  42","None;None;  G 2 986 ( 4.6A)","1.39A","4k7aA-5jbhY:undetectable","4k7aA-5jbhY:10.44"],["4K7A_A_MXDA1002_1","ANDROGEN RECEPTOR","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",3,"GLU H 128;TRP H 125;LYS H  34","None","1.04A","4k7aA-5jbhH:undetectable","4k7aA-5jbhH:21.59"],["4MX0_A_BCZA513_1","NEURAMINIDASE","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",3,"ARG H 157;ASP H  30;ARG H 133","None","0.92A","4mx0A-5jbhH:undetectable","4mx0A-5jbhH:19.23"],["5JMN_A_FUAA1101_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",4,"ILE H 188;LYS H  70;ILE H  71;VAL H 104","None;  U 21336 ( 4.1A);None;None","0.80A","5jmnA-5jbhH:undetectable","5jmnA-5jbhH:11.18"],["5V02_R_657R201_0","CALMODULIN-1;SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",5,"ALA H 126;LEU H 123;VAL H 122;LEU H  67;GLU H 187","None","1.08A","5v02B-5jbhH:undetectable;5v02R-5jbhH:undetectable","5v02B-5jbhH:21.40;5v02R-5jbhH:20.18"],["5VC0_A_RITA602_1","CYTOCHROME P450 3A4","5jbh","30S RIBOSOMAL PROTEIN US7","Pyrococcus abyssi",5,"ILE H 111;PHE H 108;ALA H 107;ILE H  71;ALA H 166","None","1.03A","5vc0A-5jbhH:undetectable","5vc0A-5jbhH:18.60"]]