SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 11 MET A 420
SER A 418
ILE A 112
ALA A  70
LEU A  68
 None
 1.14A 1jb0B-5jbkA:
undetectable		 1jb0B-5jbkA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 11 SER A 300
THR A 229
ALA A 252
ALA A 255
LEU A 168
 None
 1.09A 1jinA-5jbkA:
undetectable		 1jinA-5jbkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 12 TYR A  73
THR A 436
GLY A 434
LEU A 107
LEU A  68
 None
 1.07A 1r30A-5jbkA:
6.3		 1r30A-5jbkA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 12 TYR A  73
THR A 436
GLY A 434
LEU A 107
LEU A  68
 None
 1.07A 1r30B-5jbkA:
11.3		 1r30B-5jbkA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 8 TYR A 429
GLU A  19
GLY A  20
THR A  50
ALA A  51
 None
 1.50A 2ej3A-5jbkA:
undetectable		 2ej3A-5jbkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 11 ASN A 165
GLU A 166
TYR A 298
GLU A 367
TRP A 417
 None
GOL  A 501 (-2.9A)
GOL  A 501 (-4.1A)
GOL  A 501 (-3.8A)
GOL  A 501 (-3.9A)
 0.82A 2v3dB-5jbkA:
2.6		 2v3dB-5jbkA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 7 THR A 431
GLN A  17
ASP A 427
SER A 337
 None
GOL  A 501 ( 4.0A)
None
None
 1.19A 2xytI-5jbkA:
undetectable		 2xytI-5jbkA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 12 GLY A  87
ILE A  83
ASP A 122
LEU A 123
GLU A 139
 None
 0.99A 3o7wA-5jbkA:
undetectable		 3o7wA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 LYS A 449
ARG A 389
ASP A 377
 None
 1.35A 3o7wA-5jbkA:
undetectable		 3o7wA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 11 MET A 420
SER A 418
ILE A 112
ALA A  70
LEU A  68
 None
 1.14A 3pcqB-5jbkA:
undetectable		 3pcqB-5jbkA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 12 GLY A 202
GLY A 221
ASP A 291
TYR A 259
ILE A 258
 None
 1.08A 3prsA-5jbkA:
undetectable		 3prsA-5jbkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 GLN A   8
PHE A 115
TYR A 364
 None
 0.96A 3ucjB-5jbkA:
undetectable		 3ucjB-5jbkA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 5 LEU A  64
ALA A  70
THR A 436
PHE A  11
 None
 1.34A 3vasB-5jbkA:
undetectable		 3vasB-5jbkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 9 MET A 420
SER A 418
ILE A 112
ALA A  70
LEU A  68
 None
 1.12A 4fe1B-5jbkA:
undetectable		 4fe1B-5jbkA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.92A 4k8cA-5jbkA:
3.4		 4k8cA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.90A 4kahA-5jbkA:
3.4		 4kahA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.91A 4kahB-5jbkA:
3.2		 4kahB-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.91A 4kanA-5jbkA:
3.4		 4kanA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.93A 4kanB-5jbkA:
undetectable		 4kanB-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.93A 4kbeA-5jbkA:
3.3		 4kbeA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.94A 4kbeB-5jbkA:
3.1		 4kbeB-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.90A 4lbgA-5jbkA:
2.8		 4lbgA-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 SER A 451
TYR A 393
PRO A 448
 None
 0.90A 4lbgB-5jbkA:
3.4		 4lbgB-5jbkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 ASP A 122
TRP A 417
SER A  76
 None
GOL  A 501 (-3.9A)
None
 1.05A 4lrhB-5jbkA:
undetectable		 4lrhB-5jbkA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		5 / 10 MET A 420
SER A 418
ILE A 112
ALA A  70
LEU A  68
 None
 1.19A 4xk8B-5jbkA:
undetectable		 4xk8B-5jbkA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 ARG A 306
ARG A 245
PHE A 249
ASP A 314
 None
 1.14A 4xqgA-5jbkA:
undetectable		 4xqgA-5jbkA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 ARG A 306
ARG A 245
PHE A 249
ASP A 314
 None
 1.14A 4xqgB-5jbkA:
undetectable		 4xqgB-5jbkA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 4 ALA A 284
PRO A 257
LEU A 275
HIS A 195
 None
 1.20A 5eskA-5jbkA:
undetectable		 5eskA-5jbkA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 SER A 371
THR A 431
ARG A 341
PRO A 342
 None
 1.06A 5jhdE-5jbkA:
undetectable
5jhdG-5jbkA:
undetectable		 5jhdE-5jbkA:
19.48
5jhdG-5jbkA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 THR A 370
TYR A 298
THR A 299
ARG A 341
 None
GOL  A 501 (-4.1A)
None
None
 1.22A 5tzoA-5jbkA:
undetectable		 5tzoA-5jbkA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 THR A 370
TYR A 298
THR A 299
ARG A 341
 None
GOL  A 501 (-4.1A)
None
None
 1.21A 5tzoB-5jbkA:
undetectable		 5tzoB-5jbkA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 8 THR A 370
TYR A 298
THR A 299
ARG A 341
 None
GOL  A 501 (-4.1A)
None
None
 1.23A 5tzoC-5jbkA:
undetectable		 5tzoC-5jbkA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 7 VAL A 286
ARG A 137
GLU A 282
LEU A 275
 None
 1.06A 5umwB-5jbkA:
undetectable
5umwE-5jbkA:
undetectable		 5umwB-5jbkA:
10.96
5umwE-5jbkA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 6 GLN A   8
PHE A   7
PHE A 459
LEU A 455
 None
 1.10A 5zcoP-5jbkA:
undetectable
5zcoW-5jbkA:
undetectable		 5zcoP-5jbkA:
19.83
5zcoW-5jbkA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 6 GLN A   8
PHE A   7
PHE A 459
LEU A 455
 None
 1.12A 5zcpC-5jbkA:
undetectable
5zcpJ-5jbkA:
undetectable		 5zcpC-5jbkA:
19.83
5zcpJ-5jbkA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 6 GLN A   8
PHE A   7
PHE A 459
LEU A 455
 None
 1.13A 5zcpP-5jbkA:
undetectable
5zcpW-5jbkA:
undetectable		 5zcpP-5jbkA:
19.83
5zcpW-5jbkA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 TYR A 263
LEU A 271
ASP A 314
 None
 0.83A 5zv2B-5jbkA:
undetectable		 5zv2B-5jbkA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 7 ALA A 252
THR A 251
TYR A 254
GLN A 270
 None
 0.95A 6cduA-5jbkA:
undetectable
6cduE-5jbkA:
undetectable		 6cduA-5jbkA:
19.92
6cduE-5jbkA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		4 / 7 GLN A 270
ALA A 252
THR A 251
TYR A 254
 None
 0.93A 6cduH-5jbkA:
undetectable
6cduI-5jbkA:
undetectable		 6cduH-5jbkA:
19.92
6cduI-5jbkA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5jbk BETA-GLUCOSIDASE
(Trichoderma
harzianum) 		3 / 3 ARG A 306
ARG A 304
ASP A 320
 None
 0.98A 6d8pA-5jbkA:
1.5		 6d8pA-5jbkA:
20.40