SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jce'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		4 / 7 LEU A 175
TYR A 192
THR A  48
ASN A  74
 None
 1.36A 1afsA-5jceA:
undetectable		 1afsA-5jceA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		4 / 7 LEU A 175
TYR A 192
THR A  48
ASN A  74
 None
 1.36A 1afsB-5jceA:
undetectable		 1afsB-5jceA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		5 / 11 GLU A 196
LEU A 200
LYS A 204
ILE A 188
LEU A 217
 None
 1.23A 1jomA-5jceA:
undetectable		 1jomA-5jceA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		5 / 12 LEU A 199
PHE A 132
ILE A 216
GLY A 214
LEU A 211
 None
 1.00A 3n8xB-5jceA:
undetectable		 3n8xB-5jceA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		5 / 12 ASN A  74
GLY A 246
GLY A  75
LEU A 237
ASP A 234
 None
 1.46A 3r24A-5jceA:
undetectable		 3r24A-5jceA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		4 / 6 ALA A  84
THR A  54
VAL A  86
VAL A  59
 None
 0.94A 5eckA-5jceA:
undetectable		 5eckA-5jceA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jce CHITIN
ELICITOR-BINDING
PROTEIN
(Oryza
sativa) 		4 / 6 ALA A  84
THR A  54
VAL A  86
VAL A  59
 None
 0.92A 5eckD-5jceA:
undetectable		 5eckD-5jceA:
20.07