SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jcn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 11 LEU A 177
VAL A 221
TYR A 212
TYR A 215
PHE A 353
 None
 1.44A 1klmA-5jcnA:
undetectable		 1klmA-5jcnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 PHE A 269
ILE A 280
THR A 282
LEU A  12
THR A 123
 None
None
None
None
FAD  A 500 (-3.8A)
 1.14A 2jn3A-5jcnA:
undetectable		 2jn3A-5jcnA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		6 / 12 ALA A 319
GLY A  13
GLY A  19
LYS A  40
GLU A  95
ILE A  96
 FAD  A 500 (-3.6A)
FAD  A 500 (-3.0A)
None
FAD  A 500 (-4.7A)
None
FAD  A 500 (-4.5A)
 1.01A 2plwA-5jcnA:
2.2		 2plwA-5jcnA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 GLY A  13
GLY A  19
LYS A  40
GLU A  95
LEU A 268
 FAD  A 500 (-3.0A)
None
FAD  A 500 (-4.7A)
None
FAD  A 500 (-4.5A)
 1.08A 2plwA-5jcnA:
2.2		 2plwA-5jcnA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 TYR A 174
LEU A 203
GLY A 172
VAL A 221
PHE A 353
 NAD  A 501 (-3.6A)
None
NAD  A 501 ( 4.5A)
None
None
 1.17A 2zzmA-5jcnA:
undetectable		 2zzmA-5jcnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 TYR A 174
LEU A 203
GLY A 172
VAL A 221
PHE A 353
 NAD  A 501 (-3.6A)
None
NAD  A 501 ( 4.5A)
None
None
 1.20A 2zznA-5jcnA:
2.2		 2zznA-5jcnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 4 GLY A 173
GLY A 171
GLY A 259
GLY A 176
 NAD  A 501 (-3.5A)
NAD  A 501 ( 3.8A)
NAD  A 501 (-3.2A)
None
 0.67A 3bogC-5jcnA:
undetectable		 3bogC-5jcnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 10 ILE A  88
ILE A  37
GLY A  15
VAL A 327
LEU A  78
 None
None
FAD  A 500 (-3.2A)
None
None
 1.07A 3elzB-5jcnA:
undetectable		 3elzB-5jcnA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 10 ILE A  88
ILE A  37
GLY A  15
VAL A 327
LEU A  78
 None
None
FAD  A 500 (-3.2A)
None
None
 1.02A 3elzC-5jcnA:
undetectable		 3elzC-5jcnA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 10 ILE A  88
ILE A  37
GLY A  15
VAL A 327
LEU A  78
 None
None
FAD  A 500 (-3.2A)
None
None
 1.10A 3em0A-5jcnA:
undetectable		 3em0A-5jcnA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 6 ILE A 255
VAL A 257
LEU A 179
LEU A  56
 None
 0.80A 3kp6A-5jcnA:
undetectable
3kp6B-5jcnA:
undetectable		 3kp6A-5jcnA:
16.09
3kp6B-5jcnA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 ALA A 242
ILE A 143
ASP A 139
ALA A 138
GLN A 136
 None
 1.14A 3nvkI-5jcnA:
3.0		 3nvkI-5jcnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 8 PHE A 204
PRO A 201
GLY A 172
PHE A 194
 None
None
NAD  A 501 ( 4.5A)
None
 1.10A 3tzfB-5jcnA:
undetectable		 3tzfB-5jcnA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 12 VAL A 296
ILE A 120
GLU A  47
TYR A  20
VAL A 327
 None
 1.27A 4a97B-5jcnA:
undetectable
4a97C-5jcnA:
undetectable		 4a97B-5jcnA:
19.18
4a97C-5jcnA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		3 / 3 ALA A  17
TYR A  20
PRO A  49
 FAD  A 500 (-3.3A)
None
FAD  A 500 ( 3.6A)
 0.64A 4zdyA-5jcnA:
undetectable		 4zdyA-5jcnA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 7 GLY A  13
GLY A 124
TYR A  46
ALA A  18
 FAD  A 500 (-3.0A)
FAD  A 500 (-3.2A)
None
None
 0.86A 5e26C-5jcnA:
undetectable
5e26D-5jcnA:
undetectable		 5e26C-5jcnA:
23.24
5e26D-5jcnA:
23.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 5 GLU A  47
PRO A  49
ARG A 320
PHE A 349
ARG A 351
 None
FAD  A 500 ( 3.6A)
ASC  A 502 (-2.8A)
FAD  A 500 (-3.7A)
ASC  A 502 (-4.0A)
 0.00A 5jcnA-5jcnA:
66.9		 5jcnA-5jcnA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		6 / 6 GLU A  47
PRO A  49
GLY A  72
ARG A 320
PHE A 349
ARG A 351
 None
FAD  A 500 ( 3.6A)
ASC  A 502 (-4.0A)
ASC  A 502 (-2.8A)
FAD  A 500 (-3.7A)
ASC  A 502 (-4.0A)
 0.15A 5jcnB-5jcnA:
62.6		 5jcnB-5jcnA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 11 ILE A 255
LEU A 146
LEU A 183
ALA A 182
VAL A 240
 None
FAD  A 500 ( 4.6A)
None
None
None
 1.13A 5ji0A-5jcnA:
undetectable		 5ji0A-5jcnA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 7 LEU A 345
LEU A 429
GLY A 383
GLY A 361
 None
 0.81A 6eu9D-5jcnA:
undetectable		 6eu9D-5jcnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		4 / 8 TYR A 307
ALA A 412
VAL A 411
ASP A 343
 None
 1.03A 6hu9a-5jcnA:
undetectable
6hu9e-5jcnA:
undetectable		 6hu9a-5jcnA:
23.68
6hu9e-5jcnA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5jcn OS09G0567300 PROTEIN
(Oryza
sativa) 		5 / 10 ASP A 132
SER A 131
GLY A 176
SER A 180
VAL A 170
 None
None
None
None
NAD  A 501 (-4.8A)
 1.39A 6hu9L-5jcnA:
undetectable
6hu9P-5jcnA:
undetectable
6hu9T-5jcnA:
undetectable		 6hu9L-5jcnA:
24.44
6hu9P-5jcnA:
18.34
6hu9T-5jcnA:
10.71