SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jd3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 5jd3 LAE5
(uncultured
bacterium) 		3 / 3 GLN A  98
HIS A 108
PRO A 102
 None
 0.91A 1d8cA-5jd3A:
undetectable		 1d8cA-5jd3A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.17A 1g50B-5jd3A:
undetectable		 1g50B-5jd3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 11 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.17A 1g50C-5jd3A:
undetectable		 1g50C-5jd3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 GLY A  61
GLY A  27
ASP A  14
LEU A 121
VAL A  58
 None
None
CL  A 301 ( 4.5A)
None
None
 1.00A 2hmyB-5jd3A:
3.5		 2hmyB-5jd3A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.04A 2j7xA-5jd3A:
undetectable		 2j7xA-5jd3A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 11 TYR A   2
PHE A 208
VAL A 129
ILE A  11
PHE A   3
 None
 1.49A 2vn1A-5jd3A:
undetectable		 2vn1A-5jd3A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.04A 2yjaB-5jd3A:
undetectable		 2yjaB-5jd3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5jd3 LAE5
(uncultured
bacterium) 		4 / 8 ASP A  69
LEU A  70
GLY A  13
TYR A 114
 None
 1.00A 3af0A-5jd3A:
1.9		 3af0A-5jd3A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5jd3 LAE5
(uncultured
bacterium) 		4 / 8 ALA A 205
ILE A 204
ASN A 206
PRO A 196
 None
 1.01A 3fxrA-5jd3A:
1.7		 3fxrA-5jd3A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 10 ALA A 207
ILE A 204
ILE A  11
LEU A   9
ILE A 133
 None
 1.10A 3hbbA-5jd3A:
undetectable		 3hbbA-5jd3A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.07A 3q95A-5jd3A:
undetectable		 3q95A-5jd3A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.06A 3q95B-5jd3A:
undetectable		 3q95B-5jd3A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 ALA A 150
ASP A 172
ASP A 178
ARG A 144
ASP A 153
 SO4  A 303 (-3.2A)
None
None
None
None
 1.47A 3w37A-5jd3A:
2.1		 3w37A-5jd3A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 ALA A 150
ASP A 172
ASP A 178
ARG A 144
ASP A 153
 SO4  A 303 (-3.2A)
None
None
None
None
 1.46A 3welA-5jd3A:
2.7		 3welA-5jd3A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 ALA A 150
ASP A 172
ASP A 178
ARG A 144
ASP A 153
 SO4  A 303 (-3.2A)
None
None
None
None
 1.44A 3wemA-5jd3A:
undetectable		 3wemA-5jd3A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 ALA A 150
ASP A 172
ASP A 178
ARG A 144
ASP A 153
 SO4  A 303 (-3.2A)
None
None
None
None
 1.42A 3wenA-5jd3A:
undetectable		 3wenA-5jd3A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 ALA A 150
ASP A 172
ASP A 178
ARG A 144
ASP A 153
 SO4  A 303 (-3.2A)
None
None
None
None
 1.47A 3weoA-5jd3A:
2.3		 3weoA-5jd3A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 12 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 0.99A 4j26A-5jd3A:
undetectable		 4j26A-5jd3A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 11 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.05A 4pxmB-5jd3A:
undetectable		 4pxmB-5jd3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 10 TYR A 138
LEU A  42
ALA A  44
ALA A 205
GLY A  37
 None
 1.38A 4rn6A-5jd3A:
undetectable		 4rn6A-5jd3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 11 LEU A 158
MET A 159
ARG A 165
ILE A  90
GLY A  91
 None
 1.06A 5dxbB-5jd3A:
undetectable		 5dxbB-5jd3A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5jd3 LAE5
(uncultured
bacterium) 		4 / 7 ILE A 204
LEU A 189
ALA A 190
HIS A 201
 None
 0.95A 5hrqE-5jd3A:
undetectable
5hrqF-5jd3A:
undetectable
5hrqJ-5jd3A:
undetectable		 5hrqE-5jd3A:
20.51
5hrqF-5jd3A:
9.01
5hrqJ-5jd3A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5jd3 LAE5
(uncultured
bacterium) 		5 / 10 PHE A   3
SER A   7
GLY A   6
LEU A  46
PHE A 177
 None
 1.12A 5zjiA-5jd3A:
undetectable
5zjiJ-5jd3A:
undetectable		 5zjiA-5jd3A:
12.86
5zjiJ-5jd3A:
8.82