SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		4 / 7 GLY A  94
HIS A  95
THR A 101
ILE A 113
 None
 0.98A 1gtnF-5jd6A:
undetectable
1gtnG-5jd6A:
undetectable		 1gtnF-5jd6A:
13.60
1gtnG-5jd6A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		5 / 11 GLY A  81
GLU A   8
PHE A  79
VAL A  23
TYR A  82
 None
 1.32A 2fl5A-5jd6A:
undetectable
2fl5B-5jd6A:
undetectable
2fl5F-5jd6A:
undetectable		 2fl5A-5jd6A:
20.91
2fl5B-5jd6A:
19.03
2fl5F-5jd6A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		5 / 12 GLY A 118
ASN A 183
ILE A 113
GLY A  89
LEU A 119
 None
 1.19A 3eeyD-5jd6A:
2.1		 3eeyD-5jd6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		3 / 3 ASN A 183
HIS A 182
VAL A  66
 None
 0.91A 3elzB-5jd6A:
undetectable		 3elzB-5jd6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		5 / 12 LEU A  87
LEU A  25
GLY A  89
THR A 195
ILE A 197
 None
 1.34A 4oktA-5jd6A:
undetectable		 4oktA-5jd6A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		5 / 12 LEU A  87
LEU A  25
GLY A  94
THR A 195
ILE A 197
 None
 1.13A 4oktA-5jd6A:
undetectable		 4oktA-5jd6A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		4 / 8 THR A 114
SER A 116
GLU A 236
ASP A 203
 None
 1.21A 4qb9D-5jd6A:
undetectable		 4qb9D-5jd6A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		4 / 4 LEU A 119
GLY A 118
SER A 117
SER A 116
 None
 1.09A 5uunA-5jd6A:
undetectable		 5uunA-5jd6A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5jd6 MGS-MCHE2
(uncultured
bacterium) 		5 / 9 ASN A 183
ILE A 113
SER A 117
GLY A 115
THR A 195
 None
 1.33A 6awpA-5jd6A:
undetectable		 6awpA-5jd6A:
17.21