SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 5jdo HAPTOGLOBIN-HAEMOGLO
BIN RECEPTOR
(Trypanosoma
congolense) 		4 / 7 GLY B  33
ASP B 134
SER B  32
ALA B  26
 None
 0.98A 1gxsA-5jdoB:
3.2
1gxsB-5jdoB:
undetectable		 1gxsA-5jdoB:
22.41
1gxsB-5jdoB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 5jdo HAPTOGLOBIN-HAEMOGLO
BIN RECEPTOR
(Trypanosoma
congolense) 		5 / 11 ALA B 147
LEU B 144
LEU B   9
LEU B 182
ALA B  16
 None
 1.10A 1h9zA-5jdoB:
2.8		 1h9zA-5jdoB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 5jdo HAPTOGLOBIN-HAEMOGLO
BIN RECEPTOR
(Trypanosoma
congolense) 		4 / 6 ILE B  56
LYS B  59
ALA B  63
VAL B 101
 None
 1.02A 1hk1A-5jdoB:
3.7		 1hk1A-5jdoB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5jdo HAPTOGLOBIN-HAEMOGLO
BIN RECEPTOR
(Trypanosoma
congolense) 		5 / 11 ALA B 237
ALA B  91
ALA B 240
GLY B  60
GLY B  61
 None
 0.90A 6hwdK-5jdoB:
undetectable
6hwdL-5jdoB:
undetectable		 6hwdK-5jdoB:
17.77
6hwdL-5jdoB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5jdo HAPTOGLOBIN-HAEMOGLO
BIN RECEPTOR
(Trypanosoma
congolense) 		5 / 11 ALA B 237
ALA B  91
ALA B 240
GLY B  60
GLY B  61
 None
 0.90A 6hwdY-5jdoB:
undetectable
6hwdZ-5jdoB:
undetectable		 6hwdY-5jdoB:
17.77
6hwdZ-5jdoB:
16.58