SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jdx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5jdx PUTATIVE PEPTIDYL
CARRIER PROTEIN
(Serratia
sp.) 		4 / 5 LEU A  28
LEU A   6
ILE A  10
ALA A  11
 None
 0.76A 2i2zA-5jdxA:
undetectable		 2i2zA-5jdxA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5jdx PUTATIVE PEPTIDYL
CARRIER PROTEIN
(Serratia
sp.) 		5 / 12 PHE A  64
GLU A  58
GLN A  83
ARG A  76
SER A  50
 None
 1.40A 3apwB-5jdxA:
undetectable		 3apwB-5jdxA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5jdx PUTATIVE PEPTIDYL
CARRIER PROTEIN
(Serratia
sp.) 		3 / 3 ARG A  76
GLU A  58
ASN A  63
 None
 0.79A 4imaD-5jdxA:
undetectable		 4imaD-5jdxA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5jdx PUTATIVE PEPTIDYL
CARRIER PROTEIN
(Serratia
sp.) 		3 / 3 ARG A  76
GLU A  58
ASN A  63
 None
 0.83A 4ip7D-5jdxA:
undetectable		 4ip7D-5jdxA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5jdx PUTATIVE PEPTIDYL
CARRIER PROTEIN
(Serratia
sp.) 		4 / 8 PRO A  61
LEU A  22
ILE A  33
LEU A  46
 None
 0.84A 5ieoA-5jdxA:
undetectable		 5ieoA-5jdxA:
22.56