SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5je3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		3 / 3 SER A 133
VAL A  68
LEU A  46
 None
 0.59A 1yajG-5je3A:
undetectable		 1yajG-5je3A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		3 / 3 THR A 144
PRO A 147
TYR A 197
 None
 0.91A 2dxrA-5je3A:
undetectable		 2dxrA-5je3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 GLY A  49
ILE A  70
ASP A  95
VAL A  96
TYR A 116
 SAH  A 301 (-3.6A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.9A)
SAH  A 301 (-4.0A)
 0.71A 2qe6A-5je3A:
13.3		 2qe6A-5je3A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 GLY A  49
ILE A  70
ASP A  95
VAL A  96
TYR A 116
 SAH  A 301 (-3.6A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.9A)
SAH  A 301 (-4.0A)
 0.53A 2qe6B-5je3A:
12.9		 2qe6B-5je3A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 10 GLY A  49
ASP A  69
ILE A  70
ASP A  95
LEU A 113
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.7A)
None
 0.93A 3ay0B-5je3A:
13.8		 3ay0B-5je3A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 10 GLY A  49
ASP A  69
ILE A  70
ASP A  95
VAL A  96
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.9A)
 0.42A 3ay0B-5je3A:
13.8		 3ay0B-5je3A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
TYR A 116
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-4.0A)
 0.63A 3bxoA-5je3A:
19.7		 3bxoA-5je3A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
TYR A 116
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-4.0A)
 0.68A 3bxoB-5je3A:
18.9		 3bxoB-5je3A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ARG A  24
GLY A  49
PHE A  52
MET A  74
ALA A 111
 SAH  A 301 (-3.0A)
SAH  A 301 (-3.6A)
None
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.8A)
 0.74A 3dh0B-5je3A:
16.0		 3dh0B-5je3A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		6 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ASP A  95
ALA A 111
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.8A)
 0.65A 3ou6A-5je3A:
16.5		 3ou6A-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ALA A 111
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.8A)
 0.44A 3ou6B-5je3A:
16.5		 3ou6B-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
SER A  71
MET A  74
ASP A  95
ALA A 111
 SAH  A 301 (-3.2A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.8A)
 0.68A 3ou6C-5je3A:
16.0		 3ou6C-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ASP A  95
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 0.49A 3ou7A-5je3A:
16.3		 3ou7A-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ALA A 111
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.8A)
 0.43A 3ou7B-5je3A:
16.0		 3ou7B-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		3 / 3 GLY A  49
ASP A  69
ASP A  95
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
 0.27A 3ou7C-5je3A:
16.4		 3ou7C-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ASP A  95
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 0.52A 3ou7D-5je3A:
16.2		 3ou7D-5je3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
SER A  71
MET A  74
ASP A  95
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 0.43A 3pfgA-5je3A:
18.7		 3pfgA-5je3A:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 GLY A  49
ASP A  69
ILE A  70
MET A  74
ASP A  95
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 0.60A 4iv8A-5je3A:
17.3		 4iv8A-5je3A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 GLY A  49
ASP A  69
ILE A  70
MET A  74
ASP A  95
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 0.61A 4iv8B-5je3A:
17.4		 4iv8B-5je3A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CAD_A_ACTA402_0
(SM80.1 VICILIN)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		4 / 6 PHE A 187
ALA A 177
TYR A 116
ASN A 115
 None
None
SAH  A 301 (-4.0A)
None
 1.45A 5cadA-5je3A:
0.0		 5cadA-5je3A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		4 / 6 THR A  30
VAL A  28
VAL A 141
HIS A  33
 None
 1.07A 5eckA-5je3A:
undetectable		 5eckA-5je3A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		4 / 6 THR A  30
VAL A  28
VAL A 141
HIS A  33
 None
 1.05A 5eckD-5je3A:
undetectable		 5eckD-5je3A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ALA A  47
GLY A  49
PHE A  52
SER A  71
MET A  74
 SAH  A 301 (-3.2A)
SAH  A 301 (-3.6A)
None
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
 0.66A 5gwxA-5je3A:
20.1		 5gwxA-5je3A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 ARG A  24
GLY A  49
SER A  71
MET A  74
ASP A  95
 SAH  A 301 (-3.0A)
SAH  A 301 (-3.6A)
SAH  A 301 ( 4.8A)
SAH  A 301 ( 4.5A)
SAH  A 301 (-3.7A)
 1.02A 5hikA-5je3A:
20.5		 5hikA-5je3A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 5je3 METHYL TRANSFERASE
(Burkholderia
glumae) 		5 / 12 GLY A  49
ASP A  69
ILE A  70
VAL A  96
LEU A 113
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.9A)
SAH  A 301 (-3.7A)
SAH  A 301 (-3.9A)
None
 0.65A 5wy0A-5je3A:
14.1		 5wy0A-5je3A:
22.88