SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HMY_B_SAMB328_0 (PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI))	5jf0	PEPTIDE DEFORMYLASE (Streptococcus agalactiae)	5 / 12	GLY A 70 ASP A 15 ILE A 14 TYR A 167 VAL A 171	None SME A 16 ( 3.7A) None None None	1.01A	2hmyB-5jf0A: undetectable	2hmyB-5jf0A: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1003_0 (ALDEHYDE DEHYDROGENASE A)	5jf0	PEPTIDE DEFORMYLASE (Streptococcus agalactiae)	4 / 5	ILE A 4 LEU A 45 ASP A 18 ALA A 3	None None NI A 307 (-1.9A) None	1.04A	2opxA-5jf0A: undetectable	2opxA-5jf0A: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7B_B_HAEB1270_1 (COLLAGENASE 3)	5jf0	PEPTIDE DEFORMYLASE (Streptococcus agalactiae)	4 / 5	LEU A 53 HIS A 174 GLU A 175 HIS A 178	None NI A 302 (-3.2A) NI A 302 ( 4.3A) NI A 302 (-3.2A)	0.85A	4a7bB-5jf0A: undetectable	4a7bB-5jf0A: 19.34