SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 5jff PROBABLE ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FIC
(Escherichia
coli) 		5 / 11 LEU A 134
ILE A 131
ARG A  78
GLY A 142
LEU A  59
 None
 1.40A 2bxeA-5jffA:
undetectable		 2bxeA-5jffA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5jff PROBABLE ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FIC
(Escherichia
coli) 		4 / 4 TYR A  14
LEU A  13
LEU A  17
HIS A  27
 None
 1.47A 2x7hB-5jffA:
undetectable		 2x7hB-5jffA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jff UNCHARACTERIZED
PROTEIN YHFG
(Escherichia
coli) 		3 / 3 PRO B  33
LEU B  34
GLN B  22
 None
 0.59A 3hznG-5jffB:
undetectable
3hznH-5jffB:
undetectable		 3hznG-5jffB:
14.55
3hznH-5jffB:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5jff PROBABLE ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FIC
UNCHARACTERIZED
PROTEIN YHFG
(Escherichia
coli) 		3 / 3 GLU B  28
GLU A 168
ASN A 171
 None
 0.68A 3lp9B-5jffB:
undetectable
3lp9D-5jffB:
undetectable		 3lp9B-5jffB:
15.31
3lp9D-5jffB:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 5jff PROBABLE ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FIC
UNCHARACTERIZED
PROTEIN YHFG
(Escherichia
coli;
Escherichia
coli) 		4 / 4 LEU A  66
ILE A  70
ARG B  25
TYR A  67
 None
None
CL  B 101 (-3.0A)
CL  B 101 (-4.9A)
 1.30A 4zzcA-5jffA:
undetectable		 4zzcA-5jffA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 5jff PROBABLE ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FIC
(Escherichia
coli) 		4 / 7 LEU A  32
ALA A  35
ALA A  36
THR A  40
 None
None
CL  B 101 ( 4.0A)
CL  B 101 ( 4.8A)
 0.62A 6a7jA-5jffA:
undetectable		 6a7jA-5jffA:
19.70