SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 5jgc PROTEIN TPR1
(Oryza
sativa) 		5 / 10 ASP A  51
ASP A  95
GLU A  83
ASP A 100
GLU A  54
 None
 1.44A 1nd4A-5jgcA:
undetectable		 1nd4A-5jgcA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ND4_B_KANB2300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 5jgc PROTEIN TPR1
(Oryza
sativa) 		5 / 9 ASP A  51
ASP A  95
GLU A  83
ASP A 100
GLU A  54
 None
 1.47A 1nd4B-5jgcA:
undetectable		 1nd4B-5jgcA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5jgc PROTEIN TPR1
(Oryza
sativa) 		5 / 10 ASP A  51
ASP A  95
GLU A  83
ASP A 100
GLU A  54
 None
 1.46A 4gkiE-5jgcA:
undetectable		 4gkiE-5jgcA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5jgc PROTEIN TPR1
(Oryza
sativa) 		4 / 6 ILE A  72
ILE A  96
LEU A 101
PHE A 104
 None
 1.04A 5vkqA-5jgcA:
2.4
5vkqB-5jgcA:
2.4		 5vkqA-5jgcA:
8.14
5vkqB-5jgcA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5jgc PROTEIN TPR1
(Oryza
sativa) 		4 / 6 ILE A  72
ILE A  96
LEU A 101
PHE A 104
 None
 1.02A 5vkqA-5jgcA:
2.4
5vkqD-5jgcA:
2.5		 5vkqA-5jgcA:
8.14
5vkqD-5jgcA:
8.14