SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 LEU A  29
ASP A  36
VAL A  35
ALA A  59
VAL A  63
 None
 1.43A 2g70B-5jgjA:
9.5		 2g70B-5jgjA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 LEU A  29
ASP A  36
VAL A  35
ALA A  59
VAL A  63
 None
 1.43A 2g72A-5jgjA:
9.2		 2g72A-5jgjA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 7 LEU A 280
THR A 282
VAL A 213
TRP A 193
 None
 1.05A 2uz2A-5jgjA:
undetectable		 2uz2A-5jgjA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 PRO A 116
TYR A 120
GLY A 118
 None
 0.67A 4g2zA-5jgjA:
undetectable		 4g2zA-5jgjA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFL_B_GCSB502_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 6 GLN A 130
TRP A 162
TRP A 157
ALA A 279
 None
 1.02A 4mflA-5jgjA:
undetectable		 4mflA-5jgjA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFQ_B_GCSB503_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 6 GLN A 130
TRP A 162
TRP A 157
ALA A 279
 None
 1.08A 4mfqA-5jgjA:
0.0		 4mfqA-5jgjA:
22.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 ALA A 126
PHE A 127
GLY A 128
SER A 131
PRO A 133
 None
 0.48A 5jglA-5jgjA:
25.3		 5jglA-5jgjA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 ALA A 138
PHE A 127
GLY A 128
SER A 131
PRO A 133
 None
 1.21A 5jglA-5jgjA:
25.3		 5jglA-5jgjA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5jgj UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 ALA A 138
ALA A 126
GLY A 128
SER A 131
PRO A 133
 None
 1.30A 5jglB-5jgjA:
25.5		 5jglB-5jgjA:
100.00