SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jgp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		4 / 7 TYR A  90
VAL A  88
VAL A  95
ASN A  85
 None
 1.15A 3kmoB-5jgpA:
undetectable		 3kmoB-5jgpA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		5 / 12 HIS A  79
LEU A 102
GLY A  47
ALA A  46
LEU A 139
 None
None
NO3  A 301 (-3.2A)
None
None
 1.22A 3n8xA-5jgpA:
undetectable		 3n8xA-5jgpA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		5 / 12 PHE A 135
ALA A  40
ASP A  39
VAL A  82
LEU A  86
 None
 1.25A 3s79A-5jgpA:
undetectable		 3s79A-5jgpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		5 / 9 GLY A 209
LEU A 200
ASP A 201
LEU A 204
ASN A 203
 None
 1.33A 3wdmA-5jgpA:
undetectable		 3wdmA-5jgpA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		5 / 10 SER A  80
ALA A  77
ILE A  45
ILE A  43
LEU A 139
 None
 1.00A 4dt8B-5jgpA:
2.3		 4dt8B-5jgpA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		3 / 3 GLN A  66
HIS A  70
ARG A  55
 None
 1.08A 4qyqA-5jgpA:
undetectable		 4qyqA-5jgpA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		3 / 3 GLN A  66
HIS A  70
ARG A  55
 None
 1.01A 4qyqB-5jgpA:
undetectable		 4qyqB-5jgpA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5jgp NITRATE/NITRITE
SENSOR PROTEIN NARQ
(Escherichia
coli) 		5 / 12 PHE A 135
ALA A  40
ASP A  39
VAL A  82
LEU A  86
 None
 1.24A 5jkvA-5jgpA:
undetectable		 5jkvA-5jgpA:
18.54