SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ji5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 126
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.94A 1c3sA-5ji5A:
37.2		 1c3sA-5ji5A:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 11 PRO A  21
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.49A 1c3sA-5ji5A:
37.2		 1c3sA-5ji5A:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 ILE A 159
LEU A 149
VAL A 281
ALA A 101
ILE A 109
 None
 1.03A 1epbB-5ji5A:
undetectable		 1epbB-5ji5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 PHE A 117
GLU A  31
ILE A  30
GLY A  40
PHE A   5
 None
EDO  A 404 ( 4.6A)
None
None
None
 1.24A 1hvyC-5ji5A:
undetectable		 1hvyC-5ji5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 9 GLY A 134
PRO A  21
GLY A 286
GLY A 287
ASP A 244
 EDO  A 403 (-3.6A)
None
ZN  A 401 ( 4.2A)
None
ZN  A 401 (-2.5A)
 1.09A 1mxdA-5ji5A:
undetectable		 1mxdA-5ji5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 GLY A 134
PRO A  21
GLY A 286
GLY A 287
ASP A 244
 EDO  A 403 (-3.6A)
None
ZN  A 401 ( 4.2A)
None
ZN  A 401 (-2.5A)
 1.09A 1mxgA-5ji5A:
undetectable		 1mxgA-5ji5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 12 ASP A  83
HIS A 125
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
TYR A 288
 EDO  A 403 ( 4.6A)
None
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 0.77A 1t69A-5ji5A:
37.3		 1t69A-5ji5A:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 12 HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 0.36A 1t69A-5ji5A:
37.3		 1t69A-5ji5A:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 125
HIS A 126
ASP A 163
ASP A 244
GLY A 242
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-2.5A)
None
 1.25A 1zz1A-5ji5A:
46.7		 1zz1A-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 11 HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.42A 1zz1A-5ji5A:
46.7		 1zz1A-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 125
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.19A 1zz1A-5ji5A:
46.7		 1zz1A-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 12 HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.39A 1zz1B-5ji5A:
47.3
1zz1C-5ji5A:
47.0		 1zz1B-5ji5A:
33.69
1zz1C-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 125
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.16A 1zz1B-5ji5A:
47.3
1zz1C-5ji5A:
47.0		 1zz1B-5ji5A:
33.69
1zz1C-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 ASP A  81
GLY A 134
HIS A 125
ASP A 163
GLY A 286
 None
EDO  A 403 (-3.6A)
None
ZN  A 401 ( 2.2A)
ZN  A 401 ( 4.2A)
 1.04A 1zz1C-5ji5A:
47.0		 1zz1C-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 ASP A  81
HIS A 125
HIS A 126
GLY A 134
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.58A 1zz1C-5ji5A:
47.0		 1zz1C-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 ASP A  81
HIS A 165
GLY A 134
ASP A 244
GLY A 286
 None
ZN  A 401 (-3.1A)
EDO  A 403 (-3.6A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
 1.10A 1zz1C-5ji5A:
47.0		 1zz1C-5ji5A:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		7 / 9 HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 0.41A 1zz1D-5ji5A:
47.0		 1zz1D-5ji5A:
33.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 10 PHE A 117
GLU A  31
ILE A  30
GLY A  40
PHE A   5
 None
EDO  A 404 ( 4.6A)
None
None
None
 1.28A 2tsrC-5ji5A:
undetectable		 2tsrC-5ji5A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		4 / 7 LEU A  95
ALA A  94
PHE A 137
PHE A 138
 None
 1.07A 2vcvL-5ji5A:
undetectable		 2vcvL-5ji5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		3 / 3 SER A 119
HIS A 246
ASP A 259
 None
 0.57A 2wa2B-5ji5A:
3.0		 2wa2B-5ji5A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 PHE A 174
PRO A 234
ALA A 142
ALA A 144
THR A 105
 None
 1.20A 2x2nA-5ji5A:
undetectable		 2x2nA-5ji5A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 PHE A 174
PRO A 234
ALA A 142
ALA A 144
THR A 105
 None
 1.17A 2x2nC-5ji5A:
undetectable		 2x2nC-5ji5A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		3 / 3 HIS A 165
HIS A 126
HIS A 125
 ZN  A 401 (-3.1A)
EDO  A 403 (-4.2A)
None
 0.76A 3abmN-5ji5A:
undetectable		 3abmN-5ji5A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 5 HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
 0.15A 3c0zA-5ji5A:
44.5		 3c0zA-5ji5A:
29.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		7 / 8 HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
 None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
 0.32A 3c0zB-5ji5A:
44.7		 3c0zB-5ji5A:
29.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 6 ASP A  83
HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
 EDO  A 403 ( 4.6A)
None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
 0.61A 3c0zC-5ji5A:
44.6		 3c0zC-5ji5A:
29.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		4 / 8 PHE A 238
ILE A 159
ALA A 101
THR A 105
 None
 0.88A 3me6B-5ji5A:
undetectable		 3me6B-5ji5A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 10 ASP A  81
ASP A  83
PRO A  21
HIS A  20
GLY A 134
 None
EDO  A 403 ( 4.6A)
None
None
EDO  A 403 (-3.6A)
 1.47A 4bz6A-5ji5A:
36.7		 4bz6A-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 10 HIS A 125
HIS A 126
ASP A 163
ASP A 244
GLY A 242
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-2.5A)
None
 1.42A 4bz6A-5ji5A:
36.7		 4bz6A-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		7 / 10 HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.27A 4bz6A-5ji5A:
36.7		 4bz6A-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		7 / 12 HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.27A 4bz6A-5ji5A:
36.7
4bz6B-5ji5A:
36.6		 4bz6A-5ji5A:
23.27
4bz6B-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 12 HIS A 125
HIS A 126
GLY A 134
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.33A 4bz6C-5ji5A:
36.6		 4bz6C-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 10 ASP A  81
ASP A  83
PRO A  21
HIS A  20
GLY A 134
 None
EDO  A 403 ( 4.6A)
None
None
EDO  A 403 (-3.6A)
 1.46A 4bz6D-5ji5A:
36.8		 4bz6D-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		7 / 10 HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.25A 4bz6D-5ji5A:
36.8		 4bz6D-5ji5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 HIS A  20
PRO A  21
ASP A  83
ASP A 244
GLY A 287
TYR A 288
 None
None
EDO  A 403 ( 4.6A)
ZN  A 401 (-2.5A)
None
None
 1.41A 4lxzA-5ji5A:
39.8		 4lxzA-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		12 / 12 HIS A  20
PRO A  21
ASP A  83
HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
None
EDO  A 403 ( 4.6A)
None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.65A 4lxzA-5ji5A:
39.8		 4lxzA-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 125
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.09A 4lxzA-5ji5A:
39.8		 4lxzA-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 1.02A 4lxzA-5ji5A:
39.8		 4lxzA-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 11 HIS A  20
PRO A  21
ASP A  83
ASP A 244
GLY A 287
TYR A 288
 None
None
EDO  A 403 ( 4.6A)
ZN  A 401 (-2.5A)
None
None
 1.39A 4lxzB-5ji5A:
39.8		 4lxzB-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		11 / 11 HIS A  20
PRO A  21
ASP A  83
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
None
EDO  A 403 ( 4.6A)
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.63A 4lxzB-5ji5A:
39.8		 4lxzB-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 125
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.11A 4lxzB-5ji5A:
39.8		 4lxzB-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 PRO A  21
HIS A 126
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 1.00A 4lxzB-5ji5A:
39.8		 4lxzB-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		11 / 12 PRO A  21
ASP A  83
HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 ( 4.6A)
None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.65A 4lxzC-5ji5A:
39.8		 4lxzC-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.11A 4lxzC-5ji5A:
39.8		 4lxzC-5ji5A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.43A 4qa0A-5ji5A:
37.3		 4qa0A-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 125
HIS A 165
ASP A 244
GLY A 287
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.27A 4qa0A-5ji5A:
37.3		 4qa0A-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 126
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.98A 4qa0A-5ji5A:
37.3		 4qa0A-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		8 / 11 HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.36A 4qa0B-5ji5A:
37.2		 4qa0B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 125
PHE A 135
ASP A 244
GLY A 287
TYR A 288
 None
EDO  A 403 ( 3.8A)
ZN  A 401 (-2.5A)
None
None
 1.28A 4qa0B-5ji5A:
37.2		 4qa0B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 125
PHE A 135
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 ( 3.8A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 1.20A 4qa0B-5ji5A:
37.2		 4qa0B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 11 HIS A 126
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.99A 4qa0B-5ji5A:
37.2		 4qa0B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.34A 4qa2A-5ji5A:
37.6		 4qa2A-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 126
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.99A 4qa2A-5ji5A:
37.6		 4qa2A-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.36A 4qa2B-5ji5A:
37.7		 4qa2B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 125
HIS A 165
ASP A 244
GLY A 287
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.27A 4qa2B-5ji5A:
37.7		 4qa2B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 126
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.99A 4qa2B-5ji5A:
37.7		 4qa2B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 PHE A 135
HIS A 165
ASP A 244
GLY A 287
TYR A 288
 EDO  A 403 ( 3.8A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.21A 4qa2B-5ji5A:
37.7		 4qa2B-5ji5A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		4 / 7 MET A 254
HIS A 125
GLY A 286
HIS A 165
 None
None
ZN  A 401 ( 4.2A)
ZN  A 401 (-3.1A)
 1.31A 5a5zC-5ji5A:
undetectable		 5a5zC-5ji5A:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		10 / 12 PRO A  21
HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.26A 5eeiA-5ji5A:
45.7		 5eeiA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.99A 5eeiA-5ji5A:
45.7		 5eeiA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		10 / 12 PRO A  21
HIS A 125
HIS A 126
GLY A 134
PHE A 135
ASP A 163
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
None
EDO  A 403 (-4.2A)
EDO  A 403 (-3.6A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.24A 5eeiB-5ji5A:
45.6		 5eeiB-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.99A 5eeiB-5ji5A:
45.6		 5eeiB-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		10 / 12 HIS A  20
PRO A  21
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
None
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 0.22A 5eenA-5ji5A:
45.6		 5eenA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 HIS A  20
PRO A  21
HIS A 165
ASP A 244
GLY A 287
TYR A 288
 None
None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.12A 5eenA-5ji5A:
45.6		 5eenA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 HIS A 125
HIS A 126
ASP A 163
HIS A 165
ASP A 244
GLY A 242
 None
EDO  A 403 (-4.2A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 1.27A 5eenA-5ji5A:
45.6		 5eenA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 125
HIS A 165
ASP A 244
GLY A 286
TYR A 288
 None
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
ZN  A 401 ( 4.2A)
None
 1.12A 5eenA-5ji5A:
45.6		 5eenA-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		10 / 12 HIS A  20
PRO A  21
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
None
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.31A 5eenB-5ji5A:
45.6		 5eenB-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.10A 5eenB-5ji5A:
45.6		 5eenB-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 HIS A  20
PRO A  21
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
TYR A 288
 None
None
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 0.29A 5ef8A-5ji5A:
11.9		 5ef8A-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
 1.03A 5ef8A-5ji5A:
11.9		 5ef8A-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		9 / 12 PRO A  21
HIS A 125
HIS A 126
PHE A 135
ASP A 163
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
None
EDO  A 403 (-4.2A)
EDO  A 403 ( 3.8A)
ZN  A 401 ( 2.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 0.30A 5ef8B-5ji5A:
45.6		 5ef8B-5ji5A:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		6 / 12 PRO A  21
HIS A 126
HIS A 165
ASP A 244
LEU A 251
TYR A 288
 None
EDO  A 403 (-4.2A)
ZN  A 401 (-3.1A)
ZN  A 401 (-2.5A)
None
None
 1.09A 5ef8B-5ji5A:
45.6		 5ef8B-5ji5A:
32.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		4 / 4 CYH A 283
PHE A 117
ILE A 268
GLY A 242
 None
 1.34A 5hesB-5ji5A:
undetectable		 5hesB-5ji5A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5ji5 BUPHA.10154.A.B1
(Paraburkholderia
phymatum) 		5 / 12 HIS A 126
SER A 212
VAL A 217
ILE A 185
ASP A 161
 EDO  A 403 (-4.2A)
None
None
None
NA  A 406 (-3.4A)
 1.45A 6bxnA-5ji5A:
undetectable		 6bxnA-5ji5A:
20.69