SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		3 / 3 ARG A  37
ARG A  41
ARG A  38
 None
 0.96A 2jb7A-5jiaA:
undetectable
2jb7B-5jiaA:
undetectable
2jb7C-5jiaA:
undetectable		 2jb7A-5jiaA:
18.89
2jb7B-5jiaA:
18.89
2jb7C-5jiaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		3 / 3 ARG A  38
ARG A  37
ARG A  41
 None
 1.03A 2jb7A-5jiaA:
undetectable
2jb7B-5jiaA:
undetectable
2jb7C-5jiaA:
undetectable		 2jb7A-5jiaA:
18.89
2jb7B-5jiaA:
18.89
2jb7C-5jiaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		3 / 3 ARG A  41
ARG A  38
ARG A  37
 None
 0.94A 2jb7A-5jiaA:
undetectable
2jb7B-5jiaA:
undetectable
2jb7C-5jiaA:
undetectable		 2jb7A-5jiaA:
18.89
2jb7B-5jiaA:
18.89
2jb7C-5jiaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.32A 2zj0B-5jiaA:
undetectable		 2zj0B-5jiaA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 GLY A  67
SER A  69
GLN A  70
HIS A  76
ARG A  74
 None
 1.33A 2zthA-5jiaA:
undetectable		 2zthA-5jiaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 GLY A  67
SER A  69
GLN A  70
HIS A  76
ARG A  74
 None
 1.29A 3bwyA-5jiaA:
undetectable		 3bwyA-5jiaA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 8 GLY A 134
GLY A 141
SER A 123
SER A 139
THR A 203
 None
 0.96A 3d41A-5jiaA:
undetectable		 3d41A-5jiaA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.23A 3g1uA-5jiaA:
undetectable		 3g1uA-5jiaA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 LEU A 132
GLY A 121
GLY A 141
ILE A 169
PHE A 105
 None
 1.14A 4a6dA-5jiaA:
undetectable		 4a6dA-5jiaA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 LEU A 132
GLY A 121
GLY A 141
ILE A 169
PHE A 105
 None
 1.12A 4a6eA-5jiaA:
undetectable		 4a6eA-5jiaA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 10 LEU A 132
GLY A 205
VAL A 107
ILE A 109
VAL A 213
 None
 1.15A 4jx1B-5jiaA:
undetectable		 4jx1B-5jiaA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 VAL A  46
ALA A  45
TYR A  43
GLY A 101
THR A  51
 None
 1.36A 4mm4A-5jiaA:
undetectable		 4mm4A-5jiaA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.37A 4pfjA-5jiaA:
undetectable		 4pfjA-5jiaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.20A 4pfjB-5jiaA:
undetectable		 4pfjB-5jiaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.19A 4pgfB-5jiaA:
undetectable		 4pgfB-5jiaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 GLY A  67
SER A  69
GLN A  70
HIS A  76
ARG A  74
 None
 1.18A 5lsaA-5jiaA:
undetectable		 5lsaA-5jiaA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 5jia RAN-BINDING PROTEIN
10
(Mus
musculus) 		5 / 12 HIS A 143
ASP A 146
LEU A 132
GLY A 205
PHE A 163
 None
 1.36A 6gbnA-5jiaA:
undetectable		 6gbnA-5jiaA:
18.96