SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.44A 1d4fB-5jiuA:
undetectable		 1d4fB-5jiuA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.39A 1v8bA-5jiuA:
undetectable		 1v8bA-5jiuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.39A 1v8bB-5jiuA:
undetectable		 1v8bB-5jiuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.39A 1v8bC-5jiuA:
undetectable		 1v8bC-5jiuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.39A 1v8bD-5jiuA:
undetectable		 1v8bD-5jiuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.35A 2zj0B-5jiuA:
undetectable		 2zj0B-5jiuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.35A 2zj0D-5jiuA:
undetectable		 2zj0D-5jiuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.43A 3ce6A-5jiuA:
undetectable		 3ce6A-5jiuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.44A 3ce6B-5jiuA:
undetectable		 3ce6B-5jiuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 8 GLY A 246
GLY A 253
SER A 235
THR A 315
 None
 0.67A 3d41A-5jiuA:
undetectable		 3d41A-5jiuA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.27A 3g1uA-5jiuA:
undetectable		 3g1uA-5jiuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.43A 3n58C-5jiuA:
undetectable		 3n58C-5jiuA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.40A 3w9tA-5jiuA:
undetectable		 3w9tA-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.39A 3w9tB-5jiuA:
undetectable		 3w9tB-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.39A 3w9tC-5jiuA:
undetectable		 3w9tC-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.39A 3w9tD-5jiuA:
undetectable		 3w9tD-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.40A 3w9tE-5jiuA:
undetectable		 3w9tE-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.40A 3w9tF-5jiuA:
undetectable		 3w9tF-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 VAL A 239
GLY A 238
TYR A 313
ASP A 173
 None
 1.38A 3w9tG-5jiuA:
undetectable		 3w9tG-5jiuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 LEU A 244
GLY A 233
GLY A 253
ILE A 281
PHE A 217
 None
 1.16A 4a6dA-5jiuA:
undetectable		 4a6dA-5jiuA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 LEU A 244
GLY A 233
GLY A 253
ILE A 281
PHE A 217
 None
 1.13A 4a6eA-5jiuA:
undetectable		 4a6eA-5jiuA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 THR A 276
ILE A 221
LYS A 224
GLU A 323
 None
 1.47A 4ac9C-5jiuA:
undetectable		 4ac9C-5jiuA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		4 / 5 THR A 276
ILE A 221
LYS A 224
GLU A 323
 None
 1.50A 4acaC-5jiuA:
undetectable		 4acaC-5jiuA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 10 LEU A 244
GLY A 317
VAL A 219
ILE A 221
VAL A 325
 None
 1.21A 4jx1B-5jiuA:
undetectable		 4jx1B-5jiuA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.40A 4pfjA-5jiuA:
undetectable		 4pfjA-5jiuA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.25A 4pfjB-5jiuA:
undetectable		 4pfjB-5jiuA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.24A 4pgfB-5jiuA:
undetectable		 4pgfB-5jiuA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		3 / 3 GLU A 160
THR A 205
HIS A 206
 None
 0.70A 4q15A-5jiuA:
undetectable		 4q15A-5jiuA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		3 / 3 GLU A 160
THR A 205
HIS A 206
 None
 0.71A 4q15B-5jiuA:
undetectable		 4q15B-5jiuA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		3 / 3 GLU A 160
THR A 205
HIS A 206
 None
 0.71A 4ydqB-5jiuA:
undetectable		 4ydqB-5jiuA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.40A 5axaA-5jiuA:
undetectable		 5axaA-5jiuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5axaC-5jiuA:
undetectable		 5axaC-5jiuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.37A 5hm8A-5jiuA:
undetectable		 5hm8A-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8B-5jiuA:
undetectable		 5hm8B-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8C-5jiuA:
undetectable		 5hm8C-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8D-5jiuA:
undetectable		 5hm8D-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8E-5jiuA:
undetectable		 5hm8E-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8F-5jiuA:
undetectable		 5hm8F-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.38A 5hm8H-5jiuA:
undetectable		 5hm8H-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 SER A 235
LEU A 234
PRO A 314
TRP A 169
PHE A 217
 None
 1.40A 5jo9A-5jiuA:
undetectable		 5jo9A-5jiuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.36A 5utuF-5jiuA:
undetectable		 5utuF-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.36A 5utuH-5jiuA:
undetectable		 5utuH-5jiuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens) 		5 / 12 HIS A 255
ASP A 258
LEU A 244
GLY A 317
PHE A 275
 None
 1.39A 6gbnA-5jiuA:
undetectable		 6gbnA-5jiuA:
23.24