SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		3 / 3 GLU A 140
ILE A 208
ARG A  80
 None
 0.78A 1cd2A-5jj2A:
undetectable		 1cd2A-5jj2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		5 / 11 ILE A  93
LEU A 220
PHE A 252
GLY A 101
LYS A 100
 None
 1.35A 2bxmA-5jj2A:
undetectable		 2bxmA-5jj2A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		5 / 8 LEU A 166
LEU A 183
LEU A 193
ALA A 196
PHE A 216
 None
 1.26A 2vcvP-5jj2A:
undetectable		 2vcvP-5jj2A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		4 / 8 TYR A 275
CYH A 263
CYH A 277
TYR A 274
 MLI  A 303 ( 4.5A)
None
None
None
 1.27A 2xz5A-5jj2A:
undetectable
2xz5C-5jj2A:
undetectable		 2xz5A-5jj2A:
17.99
2xz5C-5jj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		4 / 8 TYR A 275
CYH A 263
CYH A 277
TYR A 274
 MLI  A 303 ( 4.5A)
None
None
None
 1.27A 2xz5C-5jj2A:
undetectable
2xz5D-5jj2A:
undetectable		 2xz5C-5jj2A:
17.99
2xz5D-5jj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		5 / 12 LEU A 149
ALA A 147
ILE A 145
LEU A 262
SER A 279
 None
 1.13A 3gyqA-5jj2A:
undetectable
3gyqB-5jj2A:
undetectable		 3gyqA-5jj2A:
23.36
3gyqB-5jj2A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		5 / 11 LEU A 149
ALA A 147
ILE A 145
LEU A 262
SER A 279
 None
 1.10A 3gyqB-5jj2A:
undetectable		 3gyqB-5jj2A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		4 / 7 TYR A 275
CYH A 263
CYH A 277
TYR A 274
 MLI  A 303 ( 4.5A)
None
None
None
 1.24A 3peoF-5jj2A:
0.0		 3peoF-5jj2A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		4 / 8 TYR A 275
CYH A 263
CYH A 277
TYR A 274
 MLI  A 303 ( 4.5A)
None
None
None
 1.21A 4bqtC-5jj2A:
undetectable
4bqtD-5jj2A:
undetectable		 4bqtC-5jj2A:
17.99
4bqtD-5jj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA
(Homo
sapiens) 		3 / 3 HIS A 219
LYS A 182
PHE A 180
 MLI  A 301 (-4.0A)
None
None
 1.37A 5klaA-5jj2A:
undetectable		 5klaA-5jj2A:
21.36