SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP C 158
VAL C 259
TRP C 340
 None
None
MTT  C1203 (-4.0A)
 1.24A 1c4dA-5jj4C:
undetectable
1c4dB-5jj4C:
undetectable		 1c4dA-5jj4C:
2.29
1c4dB-5jj4C:
2.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 6 VAL C   8
VAL C  50
ILE C  60
ASN C 267
 None
 0.89A 1e06A-5jj4C:
undetectable		 1e06A-5jj4C:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA C 231
ASP C 296
TYR C 210
ASN C 234
GLY C 228
 None
 1.32A 2dcfA-5jj4C:
undetectable		 2dcfA-5jj4C:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 8 ILE C1065
PHE C1061
ARG C1077
LEU C1098
 None
 0.94A 2eilN-5jj4C:
undetectable
2eilW-5jj4C:
undetectable		 2eilN-5jj4C:
21.78
2eilW-5jj4C:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 6 ASP C 197
THR C 193
LYS C 200
ASP C 358
 None
 1.20A 2j2pE-5jj4C:
undetectable
2j2pF-5jj4C:
undetectable		 2j2pE-5jj4C:
17.76
2j2pF-5jj4C:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 7 VAL C  97
ALA C 105
PHE C  92
PRO C  91
 None
 1.08A 2q6oA-5jj4C:
2.2		 2q6oA-5jj4C:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA C 264
LEU C 280
PHE C 279
VAL C 293
GLY C  16
 None
 1.11A 2ve3A-5jj4C:
undetectable		 2ve3A-5jj4C:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 11 ALA C 231
ASP C 296
TYR C 210
ASN C 234
GLY C 228
 None
 1.30A 2zmaA-5jj4C:
undetectable		 2zmaA-5jj4C:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 8 ILE C1065
PHE C1061
ARG C1077
LEU C1098
 None
 0.86A 3ablN-5jj4C:
undetectable
3ablW-5jj4C:
undetectable		 3ablN-5jj4C:
21.78
3ablW-5jj4C:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 6 ALA C 188
LEU C 192
ALA C 346
THR C 345
 None
 0.87A 3b6hA-5jj4C:
undetectable		 3b6hA-5jj4C:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 6 ALA C 188
LEU C 192
ALA C 346
THR C 345
 None
 0.90A 3b6hB-5jj4C:
undetectable		 3b6hB-5jj4C:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 6 PHE C 258
ALA C 162
LEU C 247
PRO C 159
 None
 0.96A 3bgdA-5jj4C:
undetectable		 3bgdA-5jj4C:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 7 VAL C 110
GLY C 300
PRO C 229
LYS C 305
 None
 0.71A 3bjwC-5jj4C:
undetectable		 3bjwC-5jj4C:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL C 343
GLY C 187
ALA C 188
LEU C 192
LEU C 160
 None
 0.99A 3hs6A-5jj4C:
undetectable		 3hs6A-5jj4C:
20.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		12 / 12 ASP C  14
LYS C  15
LYS C  42
GLU C  44
GLU C  45
ALA C  63
ASP C  65
ARG C  66
GLU C 111
PRO C 154
TRP C 230
TYR C 341
 MTT  C1203 (-3.2A)
MTT  C1203 (-2.8A)
MTT  C1203 (-3.5A)
MTT  C1203 (-3.1A)
MTT  C1203 (-3.4A)
MTT  C1203 (-3.3A)
MTT  C1203 (-3.0A)
MTT  C1203 (-4.3A)
MTT  C1203 (-3.0A)
MTT  C1203 (-3.6A)
MTT  C1203 (-4.5A)
MTT  C1203 (-4.5A)
 0.55A 3jyrA-5jj4C:
61.4		 3jyrA-5jj4C:
72.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN C  12
TRP C  62
GLU C 153
TYR C 155
MET C 330
TRP C 340
ARG C 344
 MTT  C1203 ( 4.8A)
MTT  C1203 (-4.1A)
MTT  C1203 (-3.5A)
MTT  C1203 (-3.9A)
MTT  C1203 (-4.2A)
MTT  C1203 (-4.0A)
MTT  C1203 (-4.1A)
 0.34A 3jyrA-5jj4C:
61.4		 3jyrA-5jj4C:
72.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 11 GLN C  49
ALA C 269
GLY C  54
THR C  53
ALA C  52
 None
 1.14A 3mg0H-5jj4C:
undetectable
3mg0I-5jj4C:
undetectable		 3mg0H-5jj4C:
20.63
3mg0I-5jj4C:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE C 156
GLY C 300
LEU C 299
GLU C 111
ALA C 231
 None
None
None
MTT  C1203 (-3.0A)
None
 0.80A 3tbgB-5jj4C:
undetectable		 3tbgB-5jj4C:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE C 156
GLY C 300
LEU C 299
GLU C 111
ALA C 231
 None
None
None
MTT  C1203 (-3.0A)
None
 0.78A 3tbgD-5jj4C:
undetectable		 3tbgD-5jj4C:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWP_A_ACAA503_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 10 ALA C 231
ASP C 296
TYR C 210
ASN C 234
GLY C 228
 None
 1.32A 3vwpA-5jj4C:
undetectable		 3vwpA-5jj4C:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA C 231
TYR C  17
TYR C 210
ASN C 234
GLY C 228
 None
 1.31A 3vwqA-5jj4C:
undetectable		 3vwqA-5jj4C:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 11 ALA C 231
ASP C 296
TYR C 210
ASN C 234
GLY C 228
 None
 1.32A 3vwrA-5jj4C:
undetectable		 3vwrA-5jj4C:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN C 267
ALA C  51
GLY C  56
ASP C  14
 None
None
None
MTT  C1203 (-3.2A)
 0.99A 4n48A-5jj4C:
undetectable		 4n48A-5jj4C:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 9 ALA C 264
ALA C 105
LEU C 103
LEU C 262
VAL C 261
 None
 1.17A 4or0B-5jj4C:
undetectable		 4or0B-5jj4C:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PRO C1086
VAL C1078
VAL C1134
PHE C1061
LEU C1029
 None
 1.45A 5cymA-5jj4C:
undetectable		 5cymA-5jj4C:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		4 / 7 ILE C1065
PHE C1061
ARG C1077
LEU C1098
 None
 0.90A 5iy5N-5jj4C:
undetectable
5iy5W-5jj4C:
undetectable		 5iy5N-5jj4C:
21.78
5iy5W-5jj4C:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLN C  49
ALA C 269
GLY C  54
THR C  53
ALA C  52
 None
 1.18A 5l66H-5jj4C:
undetectable
5l66I-5jj4C:
undetectable		 5l66H-5jj4C:
19.74
5l66I-5jj4C:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLN C  49
ALA C 269
GLY C  54
THR C  53
ALA C  52
 None
 1.18A 5l66V-5jj4C:
undetectable
5l66W-5jj4C:
undetectable		 5l66V-5jj4C:
19.74
5l66W-5jj4C:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		6 / 12 ALA C 342
ALA C 338
GLY C 166
ALA C 188
PHE C 169
VAL C 181
 None
 1.49A 5w4zA-5jj4C:
undetectable		 5w4zA-5jj4C:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR C 155
ASN C 227
LEU C 113
 MTT  C1203 (-3.9A)
None
None
 0.77A 6b58A-5jj4C:
undetectable		 6b58A-5jj4C:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 11 PRO C 133
GLU C 130
PRO C 254
ALA C 163
PRO C 159
 None
 1.40A 6bm5A-5jj4C:
undetectable		 6bm5A-5jj4C:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU C1122
LEU C1126
ARG C1127
 None
 0.76A 6d8fA-5jj4C:
3.4		 6d8fA-5jj4C:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PRO C1086
VAL C1078
VAL C1134
PHE C1061
LEU C1029
 None
 1.44A 6eliA-5jj4C:
undetectable		 6eliA-5jj4C:
8.42