SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		4 / 6 ALA A 414
LEU A 402
LEU A 444
LEU A 452
 None
 0.91A 1mt1D-5jj7A:
undetectable
1mt1E-5jj7A:
undetectable		 1mt1D-5jj7A:
15.19
1mt1E-5jj7A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		3 / 3 THR A 262
PRO A 428
TYR A 470
 None
 0.96A 2dxrA-5jj7A:
undetectable		 2dxrA-5jj7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		4 / 7 ILE A 326
LEU A 420
ALA A 396
ALA A 393
 None
 0.82A 3r9tB-5jj7A:
undetectable		 3r9tB-5jj7A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		3 / 3 LEU A 417
ILE A 421
ARG A 424
 None
 0.60A 4mk4B-5jj7A:
undetectable		 4mk4B-5jj7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		4 / 6 PHE A 264
LEU A 311
ASN A 419
ARG A 284
 None
 1.42A 4yv5B-5jj7A:
undetectable		 4yv5B-5jj7A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		4 / 6 PHE A 264
LEU A 311
ASN A 419
ARG A 284
 None
 1.37A 4yv5A-5jj7A:
undetectable		 4yv5A-5jj7A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 5jj7 ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD
HOMOLOG
(Caenorhabditis
elegans) 		4 / 5 LEU A 278
LEU A 287
THR A 270
ARG A 336
 None
 1.10A 6ew0F-5jj7A:
undetectable		 6ew0F-5jj7A:
13.09