SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 5 VAL B 525
VAL B 554
PHE B 583
ARG B 405
 PGE  B 604 ( 4.6A)
None
None
None
 1.35A 3bjwH-5jjdB:
undetectable		 3bjwH-5jjdB:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 7 PHE B 505
GLU B 372
VAL B 368
VAL B 485
 None
 1.33A 3dqrA-5jjdB:
undetectable
3dqrB-5jjdB:
undetectable		 3dqrA-5jjdB:
20.61
3dqrB-5jjdB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 VAL B 368
VAL B 485
PHE B 505
GLU B 372
 None
 1.35A 3n61A-5jjdB:
undetectable
3n61B-5jjdB:
undetectable		 3n61A-5jjdB:
20.61
3n61B-5jjdB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		3 / 3 THR B 531
VAL B 533
GLU B 498
 None
 0.69A 3v4tA-5jjdB:
undetectable
3v4tD-5jjdB:
undetectable		 3v4tA-5jjdB:
21.99
3v4tD-5jjdB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 SER B 511
ASP B 510
ARG B 366
GLU B 456
 None
 0.85A 4eysA-5jjdB:
undetectable		 4eysA-5jjdB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 ASN B 504
ILE B 464
ILE B 465
VAL B 454
 PGE  B 604 (-4.0A)
None
None
None
 0.99A 4olmA-5jjdB:
undetectable		 4olmA-5jjdB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		5 / 12 SER B 382
ASN B 556
ILE B 523
ALA B 521
VAL B 480
 None
None
PEG  B 601 ( 3.7A)
PEG  B 601 ( 3.9A)
None
 1.14A 4u95B-5jjdB:
2.1		 4u95B-5jjdB:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_H_BBIH405_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN
(Homo
sapiens) 		4 / 4 ARG B 442
GLU B 446
PHE B 579
VAL B 525
 PGE  B 604 ( 3.5A)
PGE  B 604 ( 3.4A)
PGE  B 604 (-2.7A)
PGE  B 604 ( 4.6A)
 1.34A 5h4dH-5jjdB:
0.0		 5h4dH-5jjdB:
22.18