SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 LEU A 532
VAL A 638
VAL A 699
ASP A 652
None
1.18A 1dz4A-5jjhA:
undetectable
1dz4A-5jjhA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 LEU A 532
VAL A 638
VAL A 699
ASP A 652
None
1.15A 1dz4B-5jjhA:
undetectable
1dz4B-5jjhA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
11 / 12 SER A 233
TYR A 235
GLN A 423
TRP A 425
HIS A 461
GLU A 508
HIS A 560
ASP A 561
ASN A 661
PRO A 663
TRP A 673
None
None
None
None
None
None
None
None
SO4  A 803 (-3.0A)
SO4  A 803 (-3.8A)
None
0.70A 1eswA-5jjhA:
34.0
1eswA-5jjhA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 8 GLU A 681
LEU A 695
ALA A 628
LEU A 631
None
1.00A 1hwiB-5jjhA:
undetectable
1hwiB-5jjhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 8 GLU A 681
LEU A 695
ALA A 628
LEU A 631
None
0.99A 1hwiC-5jjhA:
undetectable
1hwiC-5jjhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ALA A 369
LYS A 372
ASP A 376
ALA A 377
GOL  A 802 ( 3.7A)
None
None
None
0.37A 1iwhA-5jjhA:
undetectable
1iwhA-5jjhA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.94A 1wmqA-5jjhA:
undetectable
1wmqA-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.95A 1wmqB-5jjhA:
undetectable
1wmqB-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.95A 1wpuA-5jjhA:
undetectable
1wpuA-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.95A 1wpuB-5jjhA:
undetectable
1wpuB-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.89A 1wrqA-5jjhA:
undetectable
1wrqA-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ARG A 334
GLY A 395
ALA A 396
HIS A 392
None
0.89A 1wrqB-5jjhA:
undetectable
1wrqB-5jjhA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 569
LEU A 627
GLU A 632
GLY A 633
ALA A 606
None
1.07A 2bm9A-5jjhA:
undetectable
2bm9A-5jjhA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 569
LEU A 627
GLU A 632
GLY A 633
ALA A 606
None
1.10A 2bm9B-5jjhA:
undetectable
2bm9B-5jjhA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 569
LEU A 627
GLU A 632
GLY A 633
ALA A 606
None
1.09A 2bm9C-5jjhA:
undetectable
2bm9C-5jjhA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 569
LEU A 627
GLU A 632
GLY A 633
ALA A 606
None
1.13A 2bm9D-5jjhA:
undetectable
2bm9D-5jjhA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 4 VAL A 699
LEU A 562
ILE A 531
LEU A 532
None
1.02A 2byoA-5jjhA:
undetectable
2byoA-5jjhA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
10 / 11 SER A 233
TYR A 235
GLN A 423
TRP A 425
ASP A 460
HIS A 560
ASP A 561
ASN A 661
PRO A 663
TRP A 673
None
None
None
None
None
None
None
SO4  A 803 (-3.0A)
SO4  A 803 (-3.8A)
None
0.77A 2owcA-5jjhA:
33.3
2owcA-5jjhA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
8 / 11 SER A 233
TYR A 235
ASP A 460
HIS A 560
ASP A 561
ASN A 661
PRO A 663
TRP A 673
None
None
None
None
None
SO4  A 803 (-3.0A)
SO4  A 803 (-3.8A)
None
0.58A 2owwA-5jjhA:
33.0
2owwA-5jjhA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 11 SER A 233
TYR A 235
GLN A 423
TRP A 425
TRP A 673
None
0.73A 2owwA-5jjhA:
33.0
2owwA-5jjhA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
8 / 11 SER A 233
TYR A 235
TRP A 425
ASP A 460
HIS A 560
ASP A 561
ASN A 661
TRP A 673
None
None
None
None
None
None
SO4  A 803 (-3.0A)
None
0.72A 2owwA-5jjhA:
33.0
2owwA-5jjhA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 4 SER A  76
GLY A 158
HIS A 403
ASP A 326
None
1.37A 2oxtC-5jjhA:
undetectable
2oxtC-5jjhA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 4 SER A  76
GLY A 158
HIS A 403
ASP A 397
None
None
None
GOL  A 801 (-4.2A)
1.30A 2oxtC-5jjhA:
undetectable
2oxtC-5jjhA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
3 / 3 PRO A  96
ASN A 151
ARG A 153
None
SO4  A 811 (-3.7A)
SO4  A 811 (-2.9A)
0.88A 2qeuB-5jjhA:
undetectable
2qeuB-5jjhA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 ILE A 526
ARG A 524
LEU A 166
LEU A 465
None
1.03A 2rlfA-5jjhA:
undetectable
2rlfD-5jjhA:
undetectable
2rlfA-5jjhA:
5.18
2rlfD-5jjhA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 LEU A 532
VAL A 638
VAL A 699
ASP A 652
None
1.18A 2zawA-5jjhA:
undetectable
2zawA-5jjhA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 GLN A 423
GLY A 422
HIS A 461
TRP A 425
None
1.49A 3ai8B-5jjhA:
undetectable
3ai8B-5jjhA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 146
GLY A 158
LEU A 159
ILE A 101
ASP A 105
None
1.07A 3gwwA-5jjhA:
undetectable
3gwwA-5jjhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ASP A 386
GLY A 507
ILE A 526
ALA A 498
ILE A 506
None
0.96A 3n3iA-5jjhA:
undetectable
3n3iA-5jjhA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 7 TYR A 172
VAL A 504
ILE A 381
THR A 646
None
0.82A 3tneB-5jjhA:
undetectable
3tneB-5jjhA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ILE A 531
LEU A 562
THR A 559
GLY A 528
ASP A 509
None
1.06A 3uq6B-5jjhA:
undetectable
3uq6B-5jjhA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ILE A 531
LEU A 562
THR A 559
GLY A 528
ASP A 509
None
1.01A 3vaqA-5jjhA:
2.8
3vaqA-5jjhA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ILE A 531
LEU A 562
THR A 559
GLY A 528
ASP A 509
None
1.03A 3vaqB-5jjhA:
3.1
3vaqB-5jjhA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 7 LEU A 297
GLN A 295
PHE A 355
LEU A 359
None
0.95A 3x2qC-5jjhA:
undetectable
3x2qJ-5jjhA:
undetectable
3x2qC-5jjhA:
18.24
3x2qJ-5jjhA:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 LEU A 532
VAL A 638
VAL A 699
ASP A 652
None
1.16A 4kkyX-5jjhA:
undetectable
4kkyX-5jjhA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 7 LEU A 451
ARG A 240
PRO A 163
VAL A 491
None
GOL  A 801 (-3.7A)
None
None
1.05A 4klrA-5jjhA:
undetectable
4klrA-5jjhA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
3 / 3 VAL A  30
SER A  31
THR A  34
None
0.26A 4luhA-5jjhA:
2.5
4luhA-5jjhA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
3 / 3 ARG A 444
TRP A 143
ILE A 441
SO4  A 809 (-2.9A)
None
SO4  A 809 ( 4.8A)
0.96A 4mwxA-5jjhA:
undetectable
4mwxA-5jjhA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 VAL A 582
LEU A 580
ARG A 577
PHE A 534
None
0.96A 4o1zA-5jjhA:
undetectable
4o1zA-5jjhA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 GLN A 423
ALA A 413
LEU A 468
GLY A 390
ASP A 460
None
None
None
GOL  A 801 ( 4.3A)
None
1.17A 4qckA-5jjhA:
undetectable
4qckA-5jjhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 387
LEU A 451
LEU A 494
ALA A 503
ILE A 526
None
1.03A 4x1iD-5jjhA:
undetectable
4x1iD-5jjhA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 6 LYS A 657
PRO A 564
LEU A 569
GLU A 570
None
1.36A 4z4cA-5jjhA:
undetectable
4z4cA-5jjhA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ARG A 458
ASP A 460
GLU A 508
PHE A 534
HIS A 560
None
1.15A 5csyB-5jjhA:
32.3
5csyB-5jjhA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 ARG A 458
ASP A 460
PHE A 534
HIS A 560
ASP A 561
None
0.68A 5csyB-5jjhA:
32.3
5csyB-5jjhA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 11 LEU A 690
VAL A 187
ILE A 184
ALA A 374
ILE A 383
None
1.15A 5d75A-5jjhA:
undetectable
5d75A-5jjhA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 VAL A 648
LEU A 569
LEU A 634
SER A 703
LEU A 695
None
1.19A 5nd7B-5jjhA:
undetectable
5nd7B-5jjhA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 7 GLN A 662
LEU A 576
ALA A 566
LEU A 569
None
1.03A 5nwvA-5jjhA:
undetectable
5nwvA-5jjhA:
4.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 10 TYR A 185
TYR A 247
ILE A 248
ILE A 253
ILE A 243
None
None
None
GOL  A 802 (-4.4A)
None
1.03A 5vkqA-5jjhA:
undetectable
5vkqD-5jjhA:
undetectable
5vkqA-5jjhA:
18.36
5vkqD-5jjhA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 10 ILE A 243
TYR A 185
TYR A 247
ILE A 248
ILE A 253
None
None
None
None
GOL  A 802 (-4.4A)
1.04A 5vkqA-5jjhA:
undetectable
5vkqB-5jjhA:
undetectable
5vkqA-5jjhA:
18.36
5vkqB-5jjhA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 10 ILE A 243
TYR A 185
TYR A 247
ILE A 248
ILE A 253
None
None
None
None
GOL  A 802 (-4.4A)
1.02A 5vkqC-5jjhA:
undetectable
5vkqD-5jjhA:
undetectable
5vkqC-5jjhA:
18.36
5vkqD-5jjhA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A  35
GLY A 480
ALA A  17
PRO A 415
THR A 479
None
1.32A 5x6yC-5jjhA:
undetectable
5x6yC-5jjhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 LEU A 387
LEU A 451
LEU A 494
ALA A 503
ILE A 526
None
1.01A 5xiwB-5jjhA:
undetectable
5xiwB-5jjhA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 5 GLN A 540
ARG A 545
GLU A 600
ASP A 594
None
1.49A 5yf0A-5jjhA:
undetectable
5yf0A-5jjhA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 7 LEU A 297
GLN A 295
PHE A 355
LEU A 359
None
0.95A 5zcqP-5jjhA:
undetectable
5zcqW-5jjhA:
undetectable
5zcqP-5jjhA:
18.24
5zcqW-5jjhA:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
4 / 5 LEU A 611
TYR A 616
ILE A 574
GLY A 625
None
1.01A 6hd6A-5jjhA:
undetectable
6hd6A-5jjhA:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum)
5 / 12 PRO A 472
ILE A  38
VAL A  16
ILE A 483
PHE A 469
None
1.20A 6hlpA-5jjhA:
undetectable
6hlpA-5jjhA:
20.16