SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.13A 1c8lA-5jjoA:
undetectable		 1c8lA-5jjoA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.11A 1l5qA-5jjoA:
undetectable		 1l5qA-5jjoA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.13A 1l5qB-5jjoA:
undetectable		 1l5qB-5jjoA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.11A 1l7xA-5jjoA:
undetectable		 1l7xA-5jjoA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.09A 1l7xB-5jjoA:
undetectable		 1l7xB-5jjoA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 213
LEU A 246
LEU A 249
SER A 214
LEU A 268
 None
 0.96A 2ceoA-5jjoA:
undetectable		 2ceoA-5jjoA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 213
LEU A 246
LEU A 249
SER A 214
LEU A 268
 None
 0.96A 2ceoB-5jjoA:
undetectable		 2ceoB-5jjoA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLN A 182
LEU A 149
ASN A 151
LEU A 155
 None
AU  A 301 (-4.7A)
None
None
 1.12A 2xn3A-5jjoA:
undetectable
2xn3B-5jjoA:
undetectable		 2xn3A-5jjoA:
21.41
2xn3B-5jjoA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 213
LEU A 246
LEU A 249
SER A 214
LEU A 268
 None
 1.08A 2xn5A-5jjoA:
undetectable		 2xn5A-5jjoA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 VAL A  51
ASP A 262
TYR A  47
ASN A  83
 None
 1.01A 3avpA-5jjoA:
undetectable		 3avpA-5jjoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.14A 3bcrA-5jjoA:
undetectable		 3bcrA-5jjoA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.12A 3dd1A-5jjoA:
undetectable		 3dd1A-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.09A 3dd1B-5jjoA:
undetectable		 3dd1B-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.11A 3ddsA-5jjoA:
undetectable		 3ddsA-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.09A 3ddsB-5jjoA:
undetectable		 3ddsB-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.11A 3ddwA-5jjoA:
undetectable		 3ddwA-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.08A 3ddwB-5jjoA:
undetectable		 3ddwB-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 151
ASP A 121
ARG A  48
 None
 0.88A 3k13C-5jjoA:
undetectable		 3k13C-5jjoA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 128
ALA A 123
TYR A 120
ALA A 154
 None
 0.98A 3twpA-5jjoA:
undetectable		 3twpA-5jjoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 128
ALA A 123
TYR A 120
ALA A 154
 None
 0.94A 3twpB-5jjoA:
undetectable		 3twpB-5jjoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 128
ALA A 123
TYR A 120
ALA A 154
 None
 0.96A 3twpC-5jjoA:
undetectable		 3twpC-5jjoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 128
ALA A 123
TYR A 120
ALA A 154
 None
 1.01A 3twpD-5jjoA:
undetectable		 3twpD-5jjoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  88
SER A  86
TRP A  92
 None
 1.03A 5n8jB-5jjoA:
undetectable		 5n8jB-5jjoA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  88
SER A  86
TRP A  92
 None
 0.96A 5n8jA-5jjoA:
undetectable		 5n8jA-5jjoA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  88
SER A  86
TRP A  92
 None
 0.97A 5n8jD-5jjoA:
undetectable		 5n8jD-5jjoA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 131
ILE A 111
GLN A 117
ASP A 138
 None
 0.85A 5vlmH-5jjoA:
undetectable		 5vlmH-5jjoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5jjo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 264
PHE A 265
GLY A 216
 None
 0.65A 6fgdA-5jjoA:
undetectable		 6fgdA-5jjoA:
20.98