SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
None
 0.65A 1eizA-5jjrA:
13.8		 1eizA-5jjrA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
None
 0.69A 1ej0A-5jjrA:
12.8		 1ej0A-5jjrA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 VAL A 450
HIS A 441
CYH A 446
GLY A 447
 None
ZN  A1001 (-3.3A)
ZN  A1001 (-2.2A)
None
 0.94A 1ekjA-5jjrA:
undetectable
1ekjB-5jjrA:
undetectable		 1ekjA-5jjrA:
12.34
1ekjB-5jjrA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.81A 1fbmB-5jjrA:
undetectable		 1fbmB-5jjrA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 7 ASP A 533
ASP A 663
ASP A 664
LYS A 689
 MG  A1006 (-3.0A)
None
MG  A1006 (-2.7A)
None
 1.47A 1t03A-5jjrA:
4.4		 1t03A-5jjrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 9 THR A  34
LEU A 209
GLU A 216
LEU A 237
LEU A 204
 None
None
None
PEG  A1010 (-4.8A)
None
 1.37A 2azqA-5jjrA:
undetectable		 2azqA-5jjrA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 PHE A 398
VAL A 425
TRP A 431
 None
 0.88A 2cc8A-5jjrA:
undetectable		 2cc8A-5jjrA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 PHE A 398
VAL A 425
TRP A 431
 None
 0.89A 2ccbA-5jjrA:
undetectable		 2ccbA-5jjrA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 VAL A 164
TRP A 171
VAL A 132
 None
None
SAH  A1003 (-3.7A)
 0.84A 2izqA-5jjrA:
undetectable
2izqB-5jjrA:
undetectable		 2izqA-5jjrA:
2.83
2izqB-5jjrA:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 9 GLY A 505
SER A 504
LEU A 655
SER A 502
LEU A 380
 None
 1.35A 2j2pB-5jjrA:
undetectable
2j2pC-5jjrA:
undetectable		 2j2pB-5jjrA:
12.07
2j2pC-5jjrA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 ALA A 866
VAL A 870
ALA A 782
THR A 328
LEU A 774
 None
 1.17A 2japC-5jjrA:
5.4		 2japC-5jjrA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
VAL A 132
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
None
 0.70A 2nyuA-5jjrA:
13.9		 2nyuA-5jjrA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
VAL A 132
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
None
 0.72A 2nyuB-5jjrA:
13.9		 2nyuB-5jjrA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.8A)
 0.27A 2oxtA-5jjrA:
39.0		 2oxtA-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.8A)
 0.69A 2oxtA-5jjrA:
39.0		 2oxtA-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.67A 2oxtB-5jjrA:
39.1		 2oxtB-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
GLU A 111
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
None
 0.81A 2oxtB-5jjrA:
39.1		 2oxtB-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 SER A  56
GLY A  86
ASP A 131
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
 0.48A 2oxtB-5jjrA:
39.1		 2oxtB-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.24A 2oxtB-5jjrA:
39.1		 2oxtB-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.8A)
None
 0.45A 2oxtC-5jjrA:
38.7		 2oxtC-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
ASP A  79
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
ASP A 146
 SAH  A1003 (-3.2A)
None
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.50A 2oxtD-5jjrA:
39.0		 2oxtD-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
ASP A  79
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
None
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.98A 2oxtD-5jjrA:
39.0		 2oxtD-5jjrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.36A 2pxcA-5jjrA:
40.8		 2pxcA-5jjrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.44A 2pxcA-5jjrA:
40.8		 2pxcA-5jjrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 ILE A 735
ALA A 775
TYR A 766
LEU A 734
LEU A 839
 None
 1.01A 2rctA-5jjrA:
undetectable		 2rctA-5jjrA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 PHE A 398
VAL A 425
TRP A 431
 None
 0.87A 2vx9A-5jjrA:
undetectable		 2vx9A-5jjrA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 10 ILE A 660
ALA A 616
LEU A 681
SER A 697
THR A 612
 None
 1.11A 2w9sC-5jjrA:
undetectable		 2w9sC-5jjrA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
ASP A 131
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.44A 2wa2A-5jjrA:
33.4		 2wa2A-5jjrA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.25A 2wa2B-5jjrA:
40.0		 2wa2B-5jjrA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 SER A  56
GLY A  58
GLY A  83
THR A 104
GLU A 111
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.91A 2wa2B-5jjrA:
40.0		 2wa2B-5jjrA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 HIS A 495
LEU A 488
ILE A 552
ASN A 492
LEU A 608
 None
None
None
EDO  A1007 (-3.6A)
None
 1.11A 3cjtG-5jjrA:
8.3		 3cjtG-5jjrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 HIS A 495
LEU A 488
ILE A 552
ASN A 492
LEU A 608
 None
None
None
EDO  A1007 (-3.6A)
None
 1.06A 3cjtK-5jjrA:
undetectable		 3cjtK-5jjrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-4.2A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.44A 3eluA-5jjrA:
39.0		 3eluA-5jjrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.41A 3embA-5jjrA:
39.6		 3embA-5jjrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.54A 3embA-5jjrA:
39.6		 3embA-5jjrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.45A 3gczA-5jjrA:
40.4		 3gczA-5jjrA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLU A 653
GLY A 626
ALA A 675
GLY A 527
ASN A 676
 None
 1.32A 3jzjA-5jjrA:
undetectable		 3jzjA-5jjrA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 VAL A 132
VAL A 164
TRP A 171
 SAH  A1003 (-3.7A)
None
None
 0.87A 3l8lA-5jjrA:
undetectable
3l8lB-5jjrA:
undetectable		 3l8lA-5jjrA:
2.83
3l8lB-5jjrA:
2.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLY A 848
TRP A 331
VAL A 334
 None
 0.73A 3n62B-5jjrA:
undetectable		 3n62B-5jjrA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLY A 848
TRP A 331
VAL A 334
 None
 0.69A 3n65B-5jjrA:
undetectable		 3n65B-5jjrA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLY A 848
TRP A 331
VAL A 334
 None
 0.72A 3n66B-5jjrA:
undetectable		 3n66B-5jjrA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 ILE A 276
THR A 571
GLU A 437
GLU A 484
 None
None
ZN  A1001 (-3.1A)
None
 1.43A 3ny4A-5jjrA:
undetectable		 3ny4A-5jjrA:
14.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.50A 3p97A-5jjrA:
43.6		 3p97A-5jjrA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.49A 3p97A-5jjrA:
43.6		 3p97A-5jjrA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 3p97C-5jjrA:
43.8		 3p97C-5jjrA:
99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 9 ASP A 538
ASN A 609
GLY A 662
ASP A 663
ASP A 664
 None
None
None
None
MG  A1006 (-2.7A)
 0.89A 3sfuA-5jjrA:
20.3		 3sfuA-5jjrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 9 ASP A 538
SER A 600
GLY A 662
ASP A 663
ASP A 664
 None
None
None
None
MG  A1006 (-2.7A)
 1.15A 3sfuA-5jjrA:
20.3		 3sfuA-5jjrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 11 ASP A 538
SER A 600
ASN A 609
GLY A 662
ASP A 663
 None
 1.28A 3sfuC-5jjrA:
20.9		 3sfuC-5jjrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A 148
ILE A 179
CYH A 145
ILE A 147
LEU A 193
 None
None
None
SAH  A1003 ( 4.3A)
None
 0.96A 3uj7B-5jjrA:
8.4		 3uj7B-5jjrA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 131
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
 0.60A 4b17A-5jjrA:
12.5		 4b17A-5jjrA:
17.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.49A 4ctjA-5jjrA:
43.9		 4ctjA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
TRP A  87
LYS A 105
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.44A 4ctjA-5jjrA:
43.9		 4ctjA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.46A 4ctjC-5jjrA:
43.9		 4ctjC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.65A 4ctjC-5jjrA:
43.9		 4ctjC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
 1.13A 4ctjC-5jjrA:
43.9		 4ctjC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.40A 4ctkA-5jjrA:
43.9		 4ctkA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.33A 4ctkC-5jjrA:
44.0		 4ctkC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 SER A  56
GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.94A 4ctkC-5jjrA:
44.0		 4ctkC-5jjrA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 LYS A 747
THR A 751
ILE A 320
 None
 0.92A 4e0fB-5jjrA:
undetectable		 4e0fB-5jjrA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLU A  99
TYR A 103
GLU A 138
 None
 0.82A 4ryaA-5jjrA:
undetectable		 4ryaA-5jjrA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 SER A  56
GLY A  81
ASP A 131
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
 0.55A 4uckB-5jjrA:
6.3		 4uckB-5jjrA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 LYS A 747
ALA A 752
LEU A 754
VAL A 870
 None
 1.20A 5cr1A-5jjrA:
undetectable		 5cr1A-5jjrA:
8.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.52A 5e9qA-5jjrA:
43.5		 5e9qA-5jjrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.45A 5e9qC-5jjrA:
43.8		 5e9qC-5jjrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.24A 5ec8A-5jjrA:
43.4		 5ec8A-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
VAL A 132
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.64A 5ec8A-5jjrA:
43.4		 5ec8A-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.26A 5ec8C-5jjrA:
43.5		 5ec8C-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.85A 5ec8C-5jjrA:
43.5		 5ec8C-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5ehgA-5jjrA:
43.8		 5ehgA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.50A 5ehgA-5jjrA:
43.8		 5ehgA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.33A 5ehgC-5jjrA:
44.0		 5ehgC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.52A 5ehiA-5jjrA:
43.6		 5ehiA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.97A 5ehiA-5jjrA:
43.6		 5ehiA-5jjrA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.27A 5ehiC-5jjrA:
43.9		 5ehiC-5jjrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.32A 5ehiC-5jjrA:
43.9		 5ehiC-5jjrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.90A 5ehiC-5jjrA:
43.9		 5ehiC-5jjrA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5eifA-5jjrA:
43.8		 5eifA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.45A 5eifC-5jjrA:
43.9		 5eifC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.42A 5eiwA-5jjrA:
43.8		 5eiwA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.89A 5eiwA-5jjrA:
43.8		 5eiwA-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.23A 5eiwC-5jjrA:
44.1		 5eiwC-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.50A 5eiwC-5jjrA:
44.1		 5eiwC-5jjrA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-2.7A)
SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.51A 5ekxA-5jjrA:
43.9		 5ekxA-5jjrA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.54A 5ekxB-5jjrA:
44.0		 5ekxB-5jjrA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.3A)
 0.88A 5ekxB-5jjrA:
44.0		 5ekxB-5jjrA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ILE A 670
PHE A 674
THR A 376
TRP A 379
 None
 1.17A 5g08A-5jjrA:
undetectable		 5g08A-5jjrA:
13.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.37A 5ikmA-5jjrA:
42.8		 5ikmA-5jjrA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.46A 5ikmA-5jjrA:
42.8		 5ikmA-5jjrA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.72A 5ikmA-5jjrA:
42.8		 5ikmA-5jjrA:
52.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  83
SER A 128
ASP A 131
VAL A 132
 SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
None
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
 1.03A 5kpcB-5jjrA:
7.7		 5kpcB-5jjrA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.41A 5kqrA-5jjrA:
41.0		 5kqrA-5jjrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.29A 5kqsA-5jjrA:
40.8		 5kqsA-5jjrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5kqsA-5jjrA:
40.8		 5kqsA-5jjrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ASP A 344
ARG A 581
ASN A  69
GLN A 351
 None
None
EDO  A1012 (-3.3A)
None
 1.14A 5l6eA-5jjrA:
undetectable		 5l6eA-5jjrA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.47A 5m5bA-5jjrA:
41.3		 5m5bA-5jjrA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.67A 5m5bA-5jjrA:
41.3		 5m5bA-5jjrA:
22.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.36A 5njvA-5jjrA:
41.1		 5njvA-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.69A 5njvA-5jjrA:
41.1		 5njvA-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.44A 5njvA-5jjrA:
41.1		 5njvA-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.30A 5njvB-5jjrA:
41.0		 5njvB-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.76A 5njvB-5jjrA:
41.0		 5njvB-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.45A 5njvC-5jjrA:
40.1		 5njvC-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5njvC-5jjrA:
40.1		 5njvC-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.45A 5njvC-5jjrA:
40.1		 5njvC-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.38A 5njvD-5jjrA:
40.0		 5njvD-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.68A 5njvD-5jjrA:
40.0		 5njvD-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  83
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
 1.04A 5njvD-5jjrA:
40.0		 5njvD-5jjrA:
31.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
ASP A 146
ILE A 147
 SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.50A 5njvD-5jjrA:
40.0		 5njvD-5jjrA:
31.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 HIS A 768
HIS A 714
HIS A 712
 None
ZN  A1002 (-3.3A)
ZN  A1002 (-3.2A)
 0.96A 5oexA-5jjrA:
undetectable		 5oexA-5jjrA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLU A 158
HIS A 192
VAL A 189
 None
 0.87A 5trqB-5jjrA:
undetectable		 5trqB-5jjrA:
14.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
GLU A 111
VAL A 132
PHE A 133
ILE A 147
LYS A 180
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-4.2A)
SAH  A1003 ( 4.3A)
None
 0.53A 5vimA-5jjrA:
40.9		 5vimA-5jjrA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
LYS A 105
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-4.2A)
SAH  A1003 ( 4.3A)
None
 0.75A 5vimA-5jjrA:
40.9		 5vimA-5jjrA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
 0.39A 5vimA-5jjrA:
40.9		 5vimA-5jjrA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
LYS A 105
HIS A 110
GLU A 111
VAL A 132
PHE A 133
ILE A 147
LYS A 180
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-4.2A)
SAH  A1003 ( 4.3A)
None
 0.50A 5vimB-5jjrA:
40.9		 5vimB-5jjrA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  81
GLY A  85
HIS A 110
GLU A 111
ILE A 147
LYS A 180
 SAH  A1003 (-3.4A)
SAH  A1003 ( 4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 ( 4.3A)
None
 1.05A 5vimB-5jjrA:
40.9		 5vimB-5jjrA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A1003 (-2.7A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
 0.30A 5vimB-5jjrA:
40.9		 5vimB-5jjrA:
31.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLY A 848
TRP A 331
VAL A 334
 None
 0.68A 5vuoB-5jjrA:
undetectable		 5vuoB-5jjrA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 THR A 360
THR A 301
ARG A 594
 None
 0.98A 5wm2A-5jjrA:
undetectable		 5wm2A-5jjrA:
20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.49A 5wz1A-5jjrA:
41.2		 5wz1A-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.71A 5wz1A-5jjrA:
41.2		 5wz1A-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.50A 5wz1A-5jjrA:
41.2		 5wz1A-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 ( 4.3A)
 0.49A 5wz1B-5jjrA:
41.1		 5wz1B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
 0.70A 5wz1B-5jjrA:
41.1		 5wz1B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5wz1C-5jjrA:
40.9		 5wz1C-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.69A 5wz1C-5jjrA:
40.9		 5wz1C-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
TRP A  87
LYS A 105
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.48A 5wz1C-5jjrA:
40.9		 5wz1C-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.51A 5wz1D-5jjrA:
41.0		 5wz1D-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.70A 5wz1D-5jjrA:
41.0		 5wz1D-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.48A 5wz1E-5jjrA:
41.0		 5wz1E-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
 0.77A 5wz1E-5jjrA:
41.0		 5wz1E-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
TRP A  87
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.40A 5wz1E-5jjrA:
41.0		 5wz1E-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.50A 5wz1F-5jjrA:
41.1		 5wz1F-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
 0.68A 5wz1F-5jjrA:
41.1		 5wz1F-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.47A 5wz1G-5jjrA:
40.9		 5wz1G-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 146
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.8A)
 0.73A 5wz1G-5jjrA:
40.9		 5wz1G-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.49A 5wz1H-5jjrA:
40.9		 5wz1H-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
 0.77A 5wz1H-5jjrA:
40.9		 5wz1H-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.44A 5wz2A-5jjrA:
41.1		 5wz2A-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  58
TRP A  87
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.40A 5wz2A-5jjrA:
41.1		 5wz2A-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.34A 5wz2B-5jjrA:
41.4		 5wz2B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.54A 5wz2B-5jjrA:
41.4		 5wz2B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.46A 5wz2B-5jjrA:
41.4		 5wz2B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
TRP A  87
LYS A 105
ASP A 131
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 1.45A 5wz2B-5jjrA:
41.4		 5wz2B-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.0A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.74A 5wz2C-5jjrA:
41.1		 5wz2C-5jjrA:
63.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1003 (-3.2A)
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-3.4A)
SAH  A1003 (-4.6A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.3A)
SAH  A1003 (-3.7A)
SAH  A1003 (-3.8A)
SAH  A1003 ( 4.3A)
 0.87A 5wz2C-5jjrA:
41.1		 5wz2C-5jjrA:
63.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 GLN A 731
TRP A 331
VAL A 334
 None
 1.14A 6auuA-5jjrA:
undetectable		 6auuA-5jjrA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 ARG A 770
LYS A 719
ARG A 856
 None
 1.44A 6az3C-5jjrA:
undetectable
6az3L-5jjrA:
undetectable
6az3M-5jjrA:
undetectable		 6az3C-5jjrA:
7.15
6az3L-5jjrA:
6.78
6az3M-5jjrA:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ILE A 541
TRP A 537
ARG A 540
ASN A 613
 None
 1.19A 6hisA-5jjrA:
undetectable
6hisB-5jjrA:
undetectable		 6hisA-5jjrA:
6.39
6hisB-5jjrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ILE A 541
TRP A 537
ARG A 540
ASN A 613
 None
 1.18A 6hisB-5jjrA:
undetectable
6hisC-5jjrA:
undetectable		 6hisB-5jjrA:
6.39
6hisC-5jjrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ILE A 541
TRP A 537
ARG A 540
ASN A 613
 None
 1.17A 6hisC-5jjrA:
undetectable
6hisD-5jjrA:
undetectable		 6hisC-5jjrA:
6.39
6hisD-5jjrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ILE A 541
TRP A 537
ARG A 540
ASN A 613
 None
 1.19A 6hisD-5jjrA:
undetectable
6hisE-5jjrA:
undetectable		 6hisD-5jjrA:
6.39
6hisE-5jjrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ASN A 613
ILE A 541
TRP A 537
ARG A 540
 None
 1.17A 6hisA-5jjrA:
undetectable
6hisE-5jjrA:
undetectable		 6hisA-5jjrA:
6.39
6hisE-5jjrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5jjr GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 ASP A  79
GLY A  81
GLY A  83
LYS A 105
ASP A 131
 None
SAH  A1003 (-3.4A)
SAH  A1003 (-3.5A)
SAH  A1003 (-4.8A)
SAH  A1003 (-3.0A)
 0.52A 6nj9K-5jjrA:
6.9		 6nj9K-5jjrA:
17.73