SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 5jjw SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		3 / 3 TRP A 382
ARG A 349
THR A 378
 None
EDO  A 601 (-4.2A)
None
 1.01A 1df7A-5jjwA:
undetectable		 1df7A-5jjwA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5jjw SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 11 PHE A 333
ARG A 335
ALA A 336
ALA A 301
GLU A 299
 None
 1.09A 2bxeB-5jjwA:
3.0		 2bxeB-5jjwA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5jjw SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 5 ALA A 315
GLN A 314
ILE A 317
ARG A 349
 None
EDO  A 601 ( 4.6A)
None
EDO  A 601 (-4.2A)
 1.32A 2z0aA-5jjwA:
3.6		 2z0aA-5jjwA:
14.67