SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 12 LEU A 101
LEU A 105
ILE A 119
ASP A 111
ARG A 120
 None
 1.12A 1tw4A-5jjxA:
undetectable		 1tw4A-5jjxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 11 PHE A 210
ARG A 212
ALA A 213
ALA A 176
GLU A 174
 None
CL  A 401 (-4.1A)
None
None
None
 0.94A 2bxeB-5jjxA:
undetectable		 2bxeB-5jjxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		3 / 3 LEU A 337
VAL A 364
ARG A 370
 None
None
UNX  A 402 ( 4.0A)
 0.90A 3b0wB-5jjxA:
undetectable		 3b0wB-5jjxA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 12 ARG A 391
SER A 351
TYR A 353
VAL A 367
HIS A 368
 None
 1.44A 3g0bA-5jjxA:
undetectable		 3g0bA-5jjxA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 12 ARG A 391
SER A 351
TYR A 353
VAL A 367
HIS A 368
 None
 1.39A 3g0bC-5jjxA:
undetectable		 3g0bC-5jjxA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 6 LEU A 227
LEU A 214
SER A 215
VAL A 177
 None
None
None
UNX  A 412 ( 4.5A)
 1.12A 5a6iA-5jjxA:
undetectable		 5a6iA-5jjxA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5jjx SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 12 GLU A 204
GLY A 201
GLY A 202
VAL A 206
GLY A 196
 None
None
None
None
UNX  A 406 ( 3.8A)
 1.05A 6gneB-5jjxA:
undetectable		 6gneB-5jjxA:
21.68