SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		5 / 10 LEU A 301
GLU A 179
LEU A 175
ILE A 296
MET A 310
 None
 1.23A 1wopA-5jk0A:
undetectable		 1wopA-5jk0A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		5 / 12 LEU A 274
LEU A 220
PHE A 275
ILE A 253
THR A 233
 None
 1.19A 2v0mC-5jk0A:
undetectable		 2v0mC-5jk0A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		3 / 3 GLU A 304
HIS A 313
HIS A 174
 None
 0.74A 3co4A-5jk0A:
undetectable		 3co4A-5jk0A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		5 / 9 PHE A 136
LEU A  15
LEU A 109
ILE A 104
PHE A 112
 None
 1.01A 3tbgD-5jk0A:
undetectable		 3tbgD-5jk0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		5 / 9 PHE A 136
LEU A  15
THR A  12
LEU A 109
ILE A 104
 None
 1.02A 3tbgD-5jk0A:
undetectable		 3tbgD-5jk0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		4 / 6 LEU A 288
LEU A 203
ILE A 206
MET A 212
 None
 0.99A 4do3B-5jk0A:
undetectable		 4do3B-5jk0A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		4 / 7 ARG A 303
VAL A 208
PHE A 183
GLU A 181
 None
 1.49A 4jseA-5jk0A:
1.8
4jseB-5jk0A:
1.8		 4jseA-5jk0A:
23.32
4jseB-5jk0A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		4 / 7 PHE A 183
GLU A 181
ARG A 303
VAL A 208
 None
 1.45A 4jseA-5jk0A:
1.8
4jseB-5jk0A:
1.8		 4jseA-5jk0A:
23.32
4jseB-5jk0A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		3 / 3 ILE A 204
ASP A 188
ARG A 294
 None
 0.79A 4pstA-5jk0A:
undetectable		 4pstA-5jk0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		4 / 8 HIS A 313
ARG A 213
HIS A 335
THR A 340
 None
 1.30A 5db5A-5jk0A:
undetectable
5db5B-5jk0A:
undetectable		 5db5A-5jk0A:
23.09
5db5B-5jk0A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5jk0 TYROSINE RECOMBINASE
XERH
(Helicobacter
pylori) 		4 / 4 CYH A  61
LEU A  57
LEU A  48
ALA A  51
 None
 1.09A 5hpuA-5jk0A:
undetectable
5hpuB-5jk0A:
undetectable		 5hpuA-5jk0A:
4.79
5hpuB-5jk0A:
6.38