SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 10 PHE A  71
SER A 175
MET A 176
LEU A 343
HIS A 373
 None
 0.56A 1a8uA-5jkjA:
23.1		 1a8uA-5jkjA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 10 PHE A  71
SER A 175
MET A 176
LEU A 343
HIS A 373
 None
 0.57A 1a8uB-5jkjA:
23.1		 1a8uB-5jkjA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 0.91A 1cqeB-5jkjA:
undetectable		 1cqeB-5jkjA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 7 LEU A 391
ASP A 102
THR A 103
HIS A  76
 None
 1.12A 1v55C-5jkjA:
undetectable
1v55N-5jkjA:
undetectable
1v55P-5jkjA:
undetectable		 1v55C-5jkjA:
20.47
1v55N-5jkjA:
21.88
1v55P-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5jkj ESTERASE E22
(uncultured
bacterium) 		3 / 3 MET A 358
ASN A 320
GLN A 203
 None
 0.81A 1xoqB-5jkjA:
undetectable		 1xoqB-5jkjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.09A 2aylA-5jkjA:
undetectable		 2aylA-5jkjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.04A 2aylB-5jkjA:
undetectable		 2aylB-5jkjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 6 ILE A 172
TRP A  91
LEU A 367
ILE A 199
 None
 1.01A 2q83B-5jkjA:
undetectable		 2q83B-5jkjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.11A 3ablA-5jkjA:
undetectable
3ablC-5jkjA:
undetectable
3ablP-5jkjA:
undetectable		 3ablA-5jkjA:
21.88
3ablC-5jkjA:
20.47
3ablP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 LEU A 391
ASP A 102
THR A 103
HIS A  76
 None
 1.12A 3ablC-5jkjA:
undetectable
3ablN-5jkjA:
undetectable
3ablP-5jkjA:
undetectable		 3ablC-5jkjA:
20.47
3ablN-5jkjA:
21.88
3ablP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 6 VAL A 198
LEU A 341
ILE A  94
ILE A 335
 None
 0.73A 3gcsA-5jkjA:
undetectable		 3gcsA-5jkjA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 GLY A 376
THR A 378
SER A 175
ILE A 335
LEU A 367
 None
 1.31A 3iv6A-5jkjA:
2.6		 3iv6A-5jkjA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 9 ALA A 170
LEU A 391
VAL A 108
ILE A  94
ILE A  67
 None
 1.30A 3jw3B-5jkjA:
undetectable		 3jw3B-5jkjA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.03A 3n8wA-5jkjA:
undetectable		 3n8wA-5jkjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.04A 3n8xB-5jkjA:
undetectable		 3n8xB-5jkjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.02A 3n8zA-5jkjA:
undetectable		 3n8zA-5jkjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 ILE A 149
GLN A 180
ALA A 181
HIS A 373
ILE A  65
 None
 1.14A 3ozwB-5jkjA:
undetectable		 3ozwB-5jkjA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 0.97A 3pghA-5jkjA:
undetectable		 3pghA-5jkjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 0.98A 3pghD-5jkjA:
undetectable		 3pghD-5jkjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 237
LEU A 244
ALA A 295
ASN A 118
ILE A 219
 None
 1.08A 4o2bB-5jkjA:
2.9		 4o2bB-5jkjA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 5jkj ESTERASE E22
(uncultured
bacterium) 		3 / 3 GLY A 173
PRO A 174
GLN A 180
 None
 0.56A 4oltB-5jkjA:
undetectable		 4oltB-5jkjA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 THR A 356
SER A 357
PHE A 334
GLY A 202
LEU A 325
 None
 1.41A 4uinH-5jkjA:
undetectable
4uinL-5jkjA:
undetectable		 4uinH-5jkjA:
20.59
4uinL-5jkjA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 5jkj ESTERASE E22
(uncultured
bacterium) 		3 / 3 ASP A 299
LEU A 142
GLY A 141
 None
 0.56A 4xmfA-5jkjA:
undetectable		 4xmfA-5jkjA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 6 LEU A 160
ILE A 109
THR A  68
ALA A 181
 None
 0.79A 4zf8A-5jkjA:
undetectable		 4zf8A-5jkjA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.05A 5b1bA-5jkjA:
undetectable
5b1bC-5jkjA:
undetectable
5b1bP-5jkjA:
undetectable		 5b1bA-5jkjA:
21.88
5b1bC-5jkjA:
20.47
5b1bP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 4 CYH A 310
PHE A 313
ILE A 199
GLY A 177
 None
 1.25A 5hesB-5jkjA:
undetectable		 5hesB-5jkjA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 6 ASP A 112
ILE A 109
TYR A  54
TYR A  81
 None
 1.47A 5igyA-5jkjA:
undetectable		 5igyA-5jkjA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 304
LEU A 117
GLY A 239
SER A 243
LEU A 244
 None
 1.09A 5ikrB-5jkjA:
undetectable		 5ikrB-5jkjA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 LEU A 391
ASP A 102
THR A 103
HIS A  76
 None
 1.13A 5iy5C-5jkjA:
undetectable
5iy5N-5jkjA:
undetectable
5iy5P-5jkjA:
undetectable		 5iy5C-5jkjA:
20.75
5iy5N-5jkjA:
21.88
5iy5P-5jkjA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5jkj ESTERASE E22
(uncultured
bacterium) 		3 / 3 GLY A  98
ASP A 102
ASN A  63
 None
 0.48A 5jglA-5jkjA:
undetectable		 5jglA-5jkjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5jkj ESTERASE E22
(uncultured
bacterium) 		5 / 12 LEU A 237
LEU A 244
ALA A 295
ASN A 118
ILE A 219
 None
 1.06A 5mioB-5jkjA:
2.9		 5mioB-5jkjA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.14A 5wauA-5jkjA:
undetectable
5wauC-5jkjA:
undetectable
5wauc-5jkjA:
undetectable		 5wauA-5jkjA:
21.88
5wauC-5jkjA:
20.47
5wauc-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 7 LEU A 391
ASP A 102
THR A 103
HIS A  76
 None
 1.11A 5wauC-5jkjA:
undetectable
5waua-5jkjA:
undetectable
5wauc-5jkjA:
undetectable		 5wauC-5jkjA:
20.47
5waua-5jkjA:
21.88
5wauc-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.16A 5x19A-5jkjA:
undetectable
5x19C-5jkjA:
undetectable
5x19P-5jkjA:
undetectable		 5x19A-5jkjA:
21.88
5x19C-5jkjA:
20.47
5x19P-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 7 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.10A 5x1bA-5jkjA:
undetectable
5x1bC-5jkjA:
undetectable
5x1bP-5jkjA:
undetectable		 5x1bA-5jkjA:
21.88
5x1bC-5jkjA:
20.47
5x1bP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 7 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.15A 5x1fA-5jkjA:
undetectable
5x1fC-5jkjA:
undetectable
5x1fP-5jkjA:
undetectable		 5x1fA-5jkjA:
21.88
5x1fC-5jkjA:
20.47
5x1fP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 8 LEU A 391
ASP A 102
THR A 103
HIS A  76
 None
 1.16A 6nknC-5jkjA:
undetectable
6nknN-5jkjA:
undetectable
6nknP-5jkjA:
undetectable		 6nknC-5jkjA:
20.47
6nknN-5jkjA:
21.88
6nknP-5jkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jkj ESTERASE E22
(uncultured
bacterium) 		4 / 7 ASP A 102
THR A 103
HIS A  76
LEU A 391
 None
 1.08A 6nmfA-5jkjA:
undetectable
6nmfC-5jkjA:
undetectable
6nmfP-5jkjA:
undetectable		 6nmfA-5jkjA:
21.88
6nmfC-5jkjA:
20.47
6nmfP-5jkjA:
20.47