SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jkp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  47
ALA A  52
ALA A  54
LEU A  87
 None
 0.91A 2wx2A-5jkpA:
undetectable		 2wx2A-5jkpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLN A 182
LEU A 149
ASN A 151
LEU A 155
 None
 1.11A 2xn3A-5jkpA:
undetectable
2xn3B-5jkpA:
undetectable		 2xn3A-5jkpA:
20.95
2xn3B-5jkpA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 273
LEU A 274
GLN A 210
 None
 0.64A 3hznG-5jkpA:
undetectable
3hznH-5jkpA:
undetectable		 3hznG-5jkpA:
21.55
3hznH-5jkpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 151
ASP A 121
ARG A  48
 None
 0.90A 3k13C-5jkpA:
undetectable		 3k13C-5jkpA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 224
TYR A 240
LEU A 274
TYR A 250
 None
 1.07A 4b3qA-5jkpA:
undetectable		 4b3qA-5jkpA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 224
TYR A 240
LEU A 274
TYR A 250
 None
 0.98A 4pwdC-5jkpA:
undetectable		 4pwdC-5jkpA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 187
SER A 180
GLY A 183
ALA A 221
GLY A 217
 None
 1.20A 4r29A-5jkpA:
undetectable		 4r29A-5jkpA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 187
SER A 180
GLY A 183
ALA A 221
GLY A 217
 None
 1.18A 4r29B-5jkpA:
undetectable		 4r29B-5jkpA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 187
SER A 180
GLY A 183
ALA A 221
GLY A 217
 None
 1.21A 4r29C-5jkpA:
undetectable		 4r29C-5jkpA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 138
ALA A 136
ASP A 121
PHE A 119
GLY A 123
 None
 1.32A 5hfjE-5jkpA:
undetectable		 5hfjE-5jkpA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 138
ALA A 136
ASP A 121
PHE A 119
GLY A 123
 None
 1.29A 5hfjH-5jkpA:
undetectable		 5hfjH-5jkpA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 131
ILE A 111
GLN A 117
ASP A 138
 None
 0.92A 5vlmH-5jkpA:
undetectable		 5vlmH-5jkpA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5jkp UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 264
PHE A 265
GLY A 216
 None
 0.66A 6fgdA-5jkpA:
undetectable		 6fgdA-5jkpA:
20.86