SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jlt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.06A 1v55C-5jltA:
undetectable
1v55J-5jltA:
undetectable		 1v55C-5jltA:
16.67
1v55J-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.01A 2dysP-5jltA:
undetectable
2dysW-5jltA:
undetectable		 2dysP-5jltA:
16.67
2dysW-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.02A 2eijC-5jltA:
undetectable
2eijJ-5jltA:
undetectable		 2eijC-5jltA:
16.67
2eijJ-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 0.98A 2eimC-5jltA:
undetectable
2eimJ-5jltA:
undetectable		 2eimC-5jltA:
16.67
2eimJ-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 0.99A 2eimP-5jltA:
undetectable
2eimW-5jltA:
undetectable		 2eimP-5jltA:
16.67
2eimW-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.05A 2einC-5jltA:
undetectable
2einJ-5jltA:
undetectable		 2einC-5jltA:
16.67
2einJ-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.03A 3asnP-5jltA:
undetectable
3asnW-5jltA:
undetectable		 3asnP-5jltA:
16.67
3asnW-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		3 / 3 HIS A 170
HIS A 171
MET A 168
 None
 0.78A 3mihA-5jltA:
undetectable		 3mihA-5jltA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		3 / 3 ARG A 196
GLU A 111
THR A 107
 None
 0.80A 3v4tA-5jltA:
2.2		 3v4tA-5jltA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		5 / 12 PHE A 175
GLY A 148
GLY A 164
ILE A 172
VAL A 190
 None
 1.14A 4a6dA-5jltA:
undetectable		 4a6dA-5jltA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		5 / 12 PHE A 175
GLY A 148
GLY A 164
ILE A 172
VAL A 190
 None
 1.14A 4a6eA-5jltA:
undetectable		 4a6eA-5jltA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		3 / 3 GLY A 188
ASN A 187
ARG A 150
 None
 0.79A 5w7bD-5jltA:
undetectable		 5w7bD-5jltA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 6 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.04A 5w97C-5jltA:
undetectable
5w97J-5jltA:
undetectable		 5w97C-5jltA:
16.67
5w97J-5jltA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA
(Escherichia
virus
T4) 		4 / 7 LYS A 130
LEU A 128
LEU A 121
PHE A 152
 None
 1.03A 5x1fP-5jltA:
undetectable
5x1fW-5jltA:
undetectable		 5x1fP-5jltA:
16.67
5x1fW-5jltA:
18.18