SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jlu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 5 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.05A 1os2A-5jluA:
undetectable		 1os2A-5jluA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.04A 1os2D-5jluA:
undetectable		 1os2D-5jluA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.12A 1uttA-5jluA:
undetectable		 1uttA-5jluA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.10A 1utzA-5jluA:
undetectable		 1utzA-5jluA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.10A 1utzB-5jluA:
undetectable		 1utzB-5jluA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.05A 2hu6A-5jluA:
undetectable		 2hu6A-5jluA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.10A 2ow9B-5jluA:
undetectable		 2ow9B-5jluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.10A 2ozrC-5jluA:
undetectable		 2ozrC-5jluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.06A 2ozrD-5jluA:
undetectable		 2ozrD-5jluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.07A 2ozrE-5jluA:
undetectable		 2ozrE-5jluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 5 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.08A 3likA-5jluA:
undetectable		 3likA-5jluA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.09A 3lilA-5jluA:
undetectable		 3lilA-5jluA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 5 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.07A 3lkaA-5jluA:
undetectable		 3lkaA-5jluA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		3 / 3 HIS A  42
HIS A 108
MET A  45
 ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
None
 0.91A 3mihA-5jluA:
undetectable		 3mihA-5jluA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 6 THR A 115
VAL A 118
TYR A 119
HIS A 111
 None
 1.01A 5eckA-5jluA:
undetectable		 5eckA-5jluA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 6 THR A 115
VAL A 118
TYR A 119
HIS A 111
 None
 1.02A 5eckD-5jluA:
undetectable		 5eckD-5jluA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 6 THR A 115
VAL A 118
TYR A 119
HIS A 111
 None
 0.98A 5eclA-5jluA:
undetectable		 5eclA-5jluA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 6 THR A 115
VAL A 118
TYR A 119
HIS A 111
 None
 0.92A 5ecoA-5jluA:
undetectable		 5ecoA-5jluA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5jlu ADHESIN COMPETENCE
REPRESSOR
(Streptococcus
pyogenes) 		4 / 4 HIS A 108
GLU A  41
HIS A  42
HIS A 112
 ZN  A 201 (-3.3A)
ZN  A 201 ( 4.8A)
ZN  A 201 (-3.3A)
ZN  A 201 (-3.3A)
 1.08A 5n5jA-5jluA:
undetectable		 5n5jA-5jluA:
16.35