SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jlw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	3 / 3	TRP A 56 ARG A 53 PHE A 20	None	1.45A	1zeaH-5jlwA: undetectable 1zeaL-5jlwA: undetectable	1zeaH-5jlwA: 12.50 1zeaL-5jlwA: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_J_CHDJ101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	4 / 6	LEU A 38 ARG A 29 THR A 27 LEU A 26	None	1.08A	2dysA-5jlwA: undetectable 2dysJ-5jlwA: undetectable	2dysA-5jlwA: 7.54 2dysJ-5jlwA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	4 / 6	LEU A 38 ARG A 29 THR A 27 LEU A 26	None	1.05A	2eijA-5jlwA: undetectable 2eijJ-5jlwA: undetectable	2eijA-5jlwA: 7.54 2eijJ-5jlwA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	4 / 6	LEU A 38 ARG A 29 THR A 27 LEU A 26	None	1.05A	2eilA-5jlwA: undetectable 2eilJ-5jlwA: undetectable	2eilA-5jlwA: 7.54 2eilJ-5jlwA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	4 / 6	LEU A 38 ARG A 29 THR A 27 LEU A 26	None	1.09A	3asnA-5jlwA: undetectable 3asnJ-5jlwA: undetectable	3asnA-5jlwA: 7.54 3asnJ-5jlwA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA617_0 (SERUM ALBUMIN)	5jlw	HOMEOTIC PROTEIN ANTENNAPEDIA (Drosophila melanogaster)	3 / 3	TRP A 48 ARG A 52 LEU A 26	None	0.92A	5dbyA-5jlwA: 2.0	5dbyA-5jlwA: 6.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZEA_A_DHIA6_0","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN;MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN;SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",3,"TRP A  56;ARG A  53;PHE A  20","None","1.45A","1zeaH-5jlwA:undetectable;1zeaL-5jlwA:undetectable","1zeaH-5jlwA:12.50;1zeaL-5jlwA:14.06"],["2DYS_J_CHDJ101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",4,"LEU A  38;ARG A  29;THR A  27;LEU A  26","None","1.08A","2dysA-5jlwA:undetectable;2dysJ-5jlwA:undetectable","2dysA-5jlwA:7.54;2dysJ-5jlwA:14.29"],["2EIJ_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",4,"LEU A  38;ARG A  29;THR A  27;LEU A  26","None","1.05A","2eijA-5jlwA:undetectable;2eijJ-5jlwA:undetectable","2eijA-5jlwA:7.54;2eijJ-5jlwA:14.29"],["2EIL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",4,"LEU A  38;ARG A  29;THR A  27;LEU A  26","None","1.05A","2eilA-5jlwA:undetectable;2eilJ-5jlwA:undetectable","2eilA-5jlwA:7.54;2eilJ-5jlwA:14.29"],["3ASN_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",4,"LEU A  38;ARG A  29;THR A  27;LEU A  26","None","1.09A","3asnA-5jlwA:undetectable;3asnJ-5jlwA:undetectable","3asnA-5jlwA:7.54;3asnJ-5jlwA:14.29"],["5DBY_A_ACTA617_0","SERUM ALBUMIN","5jlw","HOMEOTIC PROTEIN ANTENNAPEDIA","Drosophila melanogaster",3,"TRP A  48;ARG A  52;LEU A  26","None","0.92A","5dbyA-5jlwA:2.0","5dbyA-5jlwA:6.92"]]