SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	5jly	THIOREDOXIN PEROXIDASE-1 (Schistosoma japonicum)	4 / 7	GLY A 125 SER A 73 PHE A 38 ARG A 147	None	0.96A	2c8aB-5jlyA: undetectable	2c8aB-5jlyA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	5jly	THIOREDOXIN PEROXIDASE-1 (Schistosoma japonicum)	4 / 7	GLY A 125 SER A 73 PHE A 38 ARG A 147	None	1.10A	2c8aD-5jlyA: undetectable	2c8aD-5jlyA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	5jly	THIOREDOXIN PEROXIDASE-1 (Schistosoma japonicum)	3 / 3	LEU A 27 ARG A 136 ASN A 66	None	0.78A	3qxvD-5jlyA: undetectable	3qxvD-5jlyA: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEE_B_RXMB601_0 (SCAFFOLD PROTEIN D13)	5jly	THIOREDOXIN PEROXIDASE-1 (Schistosoma japonicum)	5 / 9	GLN A 137 GLU A 51 PHE A 55 PHE A 127 VAL A 149	None	1.48A	6beeA-5jlyA: 0.0 6beeB-5jlyA: 0.0 6beeC-5jlyA: 0.0	6beeA-5jlyA: 15.52 6beeB-5jlyA: 15.52 6beeC-5jlyA: 15.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C8A_B_NCAB1246_0","MONO-ADP-RIBOSYLTRANSFERASE C3","5jly","THIOREDOXIN PEROXIDASE-1","Schistosoma japonicum",4,"GLY A 125;SER A  73;PHE A  38;ARG A 147","None","0.96A","2c8aB-5jlyA:undetectable","2c8aB-5jlyA:18.22"],["2C8A_D_NCAD1247_0","MONO-ADP-RIBOSYLTRANSFERASE C3","5jly","THIOREDOXIN PEROXIDASE-1","Schistosoma japonicum",4,"GLY A 125;SER A  73;PHE A  38;ARG A 147","None","1.10A","2c8aD-5jlyA:undetectable","2c8aD-5jlyA:18.22"],["3QXV_D_MTXD2000_2","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","5jly","THIOREDOXIN PEROXIDASE-1","Schistosoma japonicum",3,"LEU A  27;ARG A 136;ASN A  66","None","0.78A","3qxvD-5jlyA:undetectable","3qxvD-5jlyA:18.50"],["6BEE_B_RXMB601_0","SCAFFOLD PROTEIN D13","5jly","THIOREDOXIN PEROXIDASE-1","Schistosoma japonicum",5,"GLN A 137;GLU A  51;PHE A  55;PHE A 127;VAL A 149","None","1.48A","6beeA-5jlyA:0.0;6beeB-5jlyA:0.0;6beeC-5jlyA:0.0","6beeA-5jlyA:15.52;6beeB-5jlyA:15.52;6beeC-5jlyA:15.52"]]