SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 12 THR A 342
GLY A 340
HIS A 341
ILE A 292
VAL A 450
 None
 1.21A 1r30B-5jmuA:
3.5		 1r30B-5jmuA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		4 / 5 GLY A 401
ILE A 402
VAL A 494
SER A 395
 OCS  A 399 ( 4.2A)
OCS  A 399 ( 3.6A)
None
None
 1.20A 1rs7A-5jmuA:
undetectable		 1rs7A-5jmuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 12 THR A 479
ILE A 292
VAL A 445
ASN A 421
LEU A 483
 None
 1.35A 1wsvA-5jmuA:
undetectable		 1wsvA-5jmuA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 12 PHE A 386
GLY A 340
ALA A 337
THR A 377
ILE A 373
 None
 1.40A 3ld6B-5jmuA:
undetectable		 3ld6B-5jmuA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		4 / 5 GLY A 401
ILE A 402
VAL A 494
SER A 395
 OCS  A 399 ( 4.2A)
OCS  A 399 ( 3.6A)
None
None
 1.19A 4d33B-5jmuA:
undetectable		 4d33B-5jmuA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		4 / 5 THR A 295
THR A 319
HIS A 491
ASN A 421
 None
 1.05A 4pgfB-5jmuA:
undetectable		 4pgfB-5jmuA:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 6 ASP A 297
ASP A 298
HIS A 346
HIS A 350
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
 0.39A 5ncdA-5jmuA:
27.0
5ncdD-5jmuA:
27.2		 5ncdA-5jmuA:
31.44
5ncdD-5jmuA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 6 ASP A 297
ASP A 298
HIS A 346
HIS A 350
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
 0.40A 5ncdB-5jmuA:
27.2
5ncdC-5jmuA:
27.2		 5ncdB-5jmuA:
31.44
5ncdC-5jmuA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		4 / 4 ASP A 297
HIS A 346
HIS A 350
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
 0.26A 5ncdD-5jmuA:
27.2		 5ncdD-5jmuA:
31.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		6 / 8 ASP A 297
ASP A 298
HIS A 346
HIS A 350
PRO A 387
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
None
 0.50A 5nekB-5jmuA:
27.2		 5nekB-5jmuA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		6 / 8 ASP A 297
ASP A 298
HIS A 346
HIS A 350
TRP A 420
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
None
 0.56A 5nekD-5jmuA:
27.1		 5nekD-5jmuA:
19.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 6 ASP A 297
ASP A 298
HIS A 346
HIS A 350
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
 0.35A 5nelA-5jmuA:
27.0
5nelD-5jmuA:
27.2		 5nelA-5jmuA:
31.44
5nelD-5jmuA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		5 / 6 ASP A 297
HIS A 346
HIS A 350
LEU A 454
HIS A 456
 ZN  A 502 ( 4.8A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
None
None
 0.45A 5nelB-5jmuA:
27.2
5nelC-5jmuA:
27.0		 5nelB-5jmuA:
31.44
5nelC-5jmuA:
31.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		3 / 3 HIS A 456
ASP A 298
HIS A 346
 None
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
 0.79A 5oexB-5jmuA:
undetectable		 5oexB-5jmuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		3 / 3 HIS A 456
ASP A 298
HIS A 346
 None
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
 0.78A 5oexC-5jmuA:
undetectable		 5oexC-5jmuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5jmu PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
([Eubacterium]
rectale) 		3 / 3 HIS A 456
ASP A 298
HIS A 346
 None
ZN  A 502 (-2.6A)
ZN  A 502 (-3.3A)
 0.77A 5oexD-5jmuA:
undetectable		 5oexD-5jmuA:
19.50