SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 286
GLY A  16
LEU A 116
LEU A 292
ALA A 109
 None
 0.89A 2egvA-5jmvA:
undetectable		 2egvA-5jmvA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 286
GLY A  16
LEU A 116
LEU A 292
ALA A 109
 None
 0.89A 2egvB-5jmvA:
undetectable		 2egvB-5jmvA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		4 / 4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.64A 3bogC-5jmvA:
undetectable		 3bogC-5jmvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		4 / 4 GLY A   5
GLY A 286
GLY A  14
GLY A  16
 None
 0.59A 3bogD-5jmvA:
undetectable		 3bogD-5jmvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
UNCHARACTERIZED
PROTEIN
(Methanocaldococc
us
jannaschii;
Pyrococcus
furiosus) 		5 / 11 LEU A  95
ALA A  90
PHE A  73
ALA A  87
TYR D  29
 None
 1.22A 3bszF-5jmvA:
undetectable		 3bszF-5jmvA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
UNCHARACTERIZED
PROTEIN
(Methanocaldococc
us
jannaschii;
Pyrococcus
furiosus) 		4 / 8 SER A  82
ARG A  91
VAL A  85
TRP D  72
 None
 1.36A 3jx1A-5jmvA:
undetectable
3jx1B-5jmvA:
undetectable		 3jx1A-5jmvA:
21.23
3jx1B-5jmvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A   5
VAL A 250
ASN A  27
PHE A  26
ILE A 113
 None
 1.27A 3k13C-5jmvA:
undetectable		 3k13C-5jmvA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
UNCHARACTERIZED
PROTEIN
(Methanocaldococc
us
jannaschii;
Pyrococcus
furiosus) 		4 / 8 SER A  82
ARG A  91
VAL A  85
TRP D  72
 None
 1.38A 3nlyA-5jmvA:
undetectable
3nlyB-5jmvA:
undetectable		 3nlyA-5jmvA:
21.23
3nlyB-5jmvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
UNCHARACTERIZED
PROTEIN
(Methanocaldococc
us
jannaschii;
Pyrococcus
furiosus) 		4 / 8 SER A  82
ARG A  91
VAL A  85
TRP D  72
 None
 1.36A 3rqlA-5jmvA:
undetectable
3rqlB-5jmvA:
undetectable		 3rqlA-5jmvA:
21.23
3rqlB-5jmvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  14
THR A  29
ASN A 285
 None
 0.69A 3v4tD-5jmvA:
undetectable		 3v4tD-5jmvA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 283
ASP A 284
ILE A 289
VAL A 104
TYR A 127
 AMP  A 401 (-3.5A)
MG  A 402 ( 2.7A)
None
None
MG  A 402 (-4.7A)
 1.17A 4a81A-5jmvA:
undetectable		 4a81A-5jmvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		4 / 5 PRO A 123
ASP A 122
ILE A 136
VAL A 321
 None
 1.16A 4hytA-5jmvA:
undetectable		 4hytA-5jmvA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		3 / 3 HIS A 106
GLY A 286
ILE A 289
 MG  A 402 (-3.7A)
None
None
 0.63A 4k50A-5jmvA:
undetectable		 4k50A-5jmvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 TYR A 221
ALA A 227
TYR A 190
TYR A 226
SER A 222
 None
 1.28A 4mm4A-5jmvA:
undetectable		 4mm4A-5jmvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 TYR A 221
ALA A 227
TYR A 190
TYR A 226
SER A 222
 None
 1.25A 4mm4B-5jmvA:
undetectable		 4mm4B-5jmvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 TYR A 221
ALA A 227
TYR A 190
TYR A 226
SER A 222
 None
 1.21A 4mm6A-5jmvA:
1.7		 4mm6A-5jmvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 11 TYR A 221
ALA A 227
TYR A 190
TYR A 226
SER A 222
 None
 1.24A 4mm9A-5jmvA:
undetectable		 4mm9A-5jmvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		4 / 8 GLY A 293
GLY A   5
ILE A  71
LEU A   6
 None
 0.78A 4mwzB-5jmvA:
undetectable		 4mwzB-5jmvA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 9 LEU A 126
GLN A 134
VAL A 145
THR A 316
ILE A 108
 None
 1.34A 4pcuA-5jmvA:
undetectable
4pcuB-5jmvA:
undetectable		 4pcuA-5jmvA:
21.15
4pcuB-5jmvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 11 LEU A 126
GLN A 134
VAL A 145
THR A 316
ILE A 108
 None
 1.18A 4uuuA-5jmvA:
undetectable
4uuuB-5jmvA:
undetectable		 4uuuA-5jmvA:
21.48
4uuuB-5jmvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 11 LEU A 126
GLN A 134
VAL A 145
THR A 316
ILE A 108
 None
 1.19A 4uuuB-5jmvA:
undetectable		 4uuuB-5jmvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		4 / 5 THR A   9
HIS A  48
ALA A  10
ASP A 284
 None
None
None
MG  A 402 ( 2.7A)
 1.15A 5mfxA-5jmvA:
undetectable		 5mfxA-5jmvA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 9 MET A 230
VAL A 154
LEU A 158
ILE A 152
ASP A 151
 None
None
AMP  A 401 (-4.7A)
None
None
 1.35A 5tixA-5jmvA:
undetectable		 5tixA-5jmvA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 9 ALA A 254
LEU A 249
MET A 248
MET A 288
GLY A 114
 None
 1.49A 5wgqA-5jmvA:
undetectable		 5wgqA-5jmvA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN
(Methanocaldococc
us
jannaschii) 		5 / 12 ASP A 284
HIS A  48
LEU A  83
GLY A  76
HIS A 106
 MG  A 402 ( 2.7A)
None
None
None
MG  A 402 (-3.7A)
 1.43A 6exiD-5jmvA:
undetectable		 6exiD-5jmvA:
11.98