SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 8 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.06A 1d0vA-5jnqA:
undetectable		 1d0vA-5jnqA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 8 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.07A 1jhaA-5jnqA:
undetectable		 1jhaA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.07A 1jhoA-5jnqA:
undetectable		 1jhoA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.09A 1jhrA-5jnqA:
undetectable		 1jhrA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.08A 1jhyA-5jnqA:
undetectable		 1jhyA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.08A 1l4nA-5jnqA:
undetectable		 1l4nA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.10A 1l5kA-5jnqA:
undetectable		 1l5kA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.11A 1l5lA-5jnqA:
undetectable		 1l5lA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.12A 1l5mA-5jnqA:
undetectable		 1l5mA-5jnqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 ASN A 172
ASP A 168
ILE A 118
GLY A  90
ILE A  89
 TUM  A 401 (-3.4A)
None
None
None
None
 1.49A 1q8jA-5jnqA:
undetectable		 1q8jA-5jnqA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		4 / 5 LEU A 177
ASP A 175
MET A 286
LEU A 295
 None
TUM  A 401 (-3.6A)
None
None
 1.24A 2qxsA-5jnqA:
undetectable		 2qxsA-5jnqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 GLY A 212
ILE A  10
ALA A   8
PHE A 217
THR A 182
 None
 1.08A 2vdvE-5jnqA:
undetectable		 2vdvE-5jnqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 11 GLY A 212
ILE A  10
ALA A   8
PHE A 217
THR A 182
 None
 1.08A 2vdvF-5jnqA:
undetectable		 2vdvF-5jnqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 10 VAL A 241
PHE A 240
ILE A 257
GLY A 258
THR A 311
 None
 1.26A 3t3rD-5jnqA:
undetectable		 3t3rD-5jnqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		3 / 3 LEU A 137
MET A 248
ASP A 200
 None
 0.80A 3v5wA-5jnqA:
undetectable		 3v5wA-5jnqA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 ILE A 257
ALA A 189
ILE A 194
PHE A 191
LEU A 322
 None
None
PLM  A 402 ( 4.6A)
None
None
 1.09A 4cd2A-5jnqA:
undetectable		 4cd2A-5jnqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 ILE A  57
GLY A  55
GLY A  54
SER A  16
THR A 182
 None
 1.06A 4kadA-5jnqA:
undetectable		 4kadA-5jnqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 9 GLY A 216
PHE A 217
LEU A 214
SER A  16
GLY A 212
 None
 1.03A 4kqiA-5jnqA:
undetectable		 4kqiA-5jnqA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 ILE A  57
GLY A  55
GLY A  54
SER A  16
THR A 182
 None
 1.05A 4lc4A-5jnqA:
undetectable		 4lc4A-5jnqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 TYR A  73
GLY A 208
ILE A 206
ILE A   6
ALA A   8
 None
 1.09A 4qtuB-5jnqA:
undetectable		 4qtuB-5jnqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 GLN A 115
ILE A 118
VAL A  82
GLY A 120
PHE A 122
 None
 1.15A 5ergB-5jnqA:
undetectable		 5ergB-5jnqA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		4 / 7 ALA A   8
THR A  65
ILE A  15
ALA A  14
 None
 0.96A 6ma7A-5jnqA:
undetectable		 6ma7A-5jnqA:
11.96