SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 6 ARG A  40
ILE A  77
PHE A  85
GLU A  80
 None
 1.45A 1nsiA-5jnuA:
undetectable
1nsiB-5jnuA:
undetectable		 1nsiA-5jnuA:
15.96
1nsiB-5jnuA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 6 PHE A  85
GLU A  80
ARG A  40
ILE A  77
 None
 1.42A 1nsiA-5jnuA:
undetectable
1nsiB-5jnuA:
undetectable		 1nsiA-5jnuA:
15.96
1nsiB-5jnuA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 6 ARG A  40
ILE A  77
PHE A  85
GLU A  80
 None
 1.46A 1nsiC-5jnuA:
undetectable
1nsiD-5jnuA:
undetectable		 1nsiC-5jnuA:
15.96
1nsiD-5jnuA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 7 ARG A  40
ILE A  77
PHE A  85
GLU A  80
 None
 1.50A 2nsiA-5jnuA:
undetectable
2nsiB-5jnuA:
undetectable		 2nsiA-5jnuA:
15.96
2nsiB-5jnuA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 7 PHE A  85
GLU A  80
ARG A  40
ILE A  77
 None
 1.46A 2nsiA-5jnuA:
undetectable
2nsiB-5jnuA:
undetectable		 2nsiA-5jnuA:
15.96
2nsiB-5jnuA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 7 ARG A  40
ILE A  77
PHE A  85
GLU A  80
 None
 1.43A 3e7gC-5jnuA:
undetectable
3e7gD-5jnuA:
undetectable		 3e7gC-5jnuA:
16.71
3e7gD-5jnuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 8 PHE A  85
GLU A  80
ARG A  40
ILE A  77
 None
 1.43A 3e7gC-5jnuA:
undetectable
3e7gD-5jnuA:
undetectable		 3e7gC-5jnuA:
16.71
3e7gD-5jnuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 5 ASP A 129
GLU A  50
GLY A  14
ASP A  92
 None
 1.00A 3w9tD-5jnuA:
undetectable		 3w9tD-5jnuA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 7 PHE A  85
GLU A  80
ARG A  40
ILE A  77
 None
 1.44A 4nosA-5jnuA:
undetectable
4nosB-5jnuA:
undetectable		 4nosA-5jnuA:
16.71
4nosB-5jnuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 7 ARG A  40
ILE A  77
PHE A  85
GLU A  80
 None
 1.36A 4nosC-5jnuA:
undetectable
4nosD-5jnuA:
undetectable		 4nosC-5jnuA:
16.71
4nosD-5jnuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5jnu LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Mus
musculus) 		4 / 6 PHE A  85
GLU A  80
ARG A  40
ILE A  77
 None
 1.40A 4nosC-5jnuA:
undetectable
4nosD-5jnuA:
undetectable		 4nosC-5jnuA:
16.71
4nosD-5jnuA:
16.71