SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5joq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		5 / 9 LEU A  53
LEU A  51
ILE A  47
LEU A  95
ILE A  37
 None
 1.14A 2f7aB-5joqA:
undetectable		 2f7aB-5joqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ALA A  39
LEU A  95
THR A  97
PHE A 120
GLN A 127
 None
None
CL  A 302 (-4.1A)
None
None
 1.25A 2jjpA-5joqA:
undetectable		 2jjpA-5joqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		5 / 12 PRO A  66
ILE A  47
LEU A  51
ALA A 143
LEU A 150
 None
 1.15A 3a50A-5joqA:
undetectable		 3a50A-5joqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASN A 266
ASN A 275
GLU A 278
 None
 0.86A 3kpdB-5joqA:
undetectable		 3kpdB-5joqA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		6 / 12 ILE A  37
THR A  40
GLY A 107
ALA A 115
ASP A 116
PHE A 117
 None
 0.92A 3oxzA-5joqA:
undetectable		 3oxzA-5joqA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 5joq LMO2184 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LEU A 133
MET A 126
ILE A 140
LEU A 146
 None
 1.30A 5nfpA-5joqA:
undetectable		 5nfpA-5joqA:
22.52