SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 116
PRO B 118
THR B 117
PRO B 147
 None
 1.19A 1dsdC-5jorB:
undetectable		 1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 117
PRO B 147
THR B 116
PRO B 118
 None
 1.15A 1dsdC-5jorB:
undetectable		 1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 116
PRO B 118
THR B 117
PRO B 147
 None
 1.19A 1dsdC-5jorB:
undetectable		 1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 117
PRO B 147
THR B 116
PRO B 118
 None
 1.15A 1dsdC-5jorB:
undetectable		 1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 HIS B  82
ALA B  67
PHE B  63
GLY B  65
 None
 1.20A 1mj2B-5jorB:
undetectable		 1mj2B-5jorB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 HIS B  82
ALA B  67
PHE B  63
GLY B  65
 None
 1.25A 1mj2D-5jorB:
undetectable		 1mj2D-5jorB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 HIS B  82
ALA B  67
PHE B  63
GLY B  65
 None
 1.20A 1mjoB-5jorB:
undetectable		 1mjoB-5jorB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 4 HIS B  82
ALA B  67
PHE B  63
GLY B  65
 None
 1.15A 1mjoA-5jorB:
undetectable		 1mjoA-5jorB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY B  42
ILE B  40
GLN B  41
SER B  44
 1PE  B 309 ( 3.9A)
None
1PE  B 310 ( 3.5A)
None
 1.07A 4kcnA-5jorB:
undetectable		 4kcnA-5jorB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 5jor FAB14.22 HEAVY CHAIN
(Mus
musculus) 		4 / 6 MET B  80
ASN B  76
VAL B  71
LEU B  69
 None
 0.94A 5xdhA-5jorB:
undetectable
5xdhC-5jorB:
undetectable		 5xdhA-5jorB:
14.77
5xdhC-5jorB:
14.77