SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 6 ILE A 139
GLU A 189
ASP A  34
PRO A  95
 TRS  A 601 (-4.8A)
EDO  A 603 ( 2.9A)
TRS  A 601 (-2.8A)
None
 1.20A 1ditH-5jowA:
undetectable
1ditP-5jowA:
undetectable		 1ditH-5jowA:
20.52
1ditP-5jowA:
3.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 6 VAL A 427
GLY A 428
LEU A 415
GLU A 452
 None
 0.98A 1fduD-5jowA:
undetectable		 1fduD-5jowA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		5 / 12 CYH A 163
GLU A 135
ASP A 166
GLY A 170
ILE A 107
 None
None
None
EDO  A 608 ( 4.7A)
None
 1.36A 1oltA-5jowA:
undetectable		 1oltA-5jowA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		5 / 12 HIS A 213
GLY A 252
SER A  50
ASP A 140
VAL A 215
 None
None
None
TRS  A 601 (-3.0A)
None
 1.47A 1qu3A-5jowA:
undetectable		 1qu3A-5jowA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 8 GLY A 252
THR A 251
ALA A 270
VAL A  27
 None
 0.74A 2a1hA-5jowA:
undetectable
2a1hB-5jowA:
undetectable		 2a1hA-5jowA:
23.29
2a1hB-5jowA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		3 / 3 THR A  76
PRO A  78
PRO A  55
 None
 0.90A 2d55C-5jowA:
undetectable		 2d55C-5jowA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		5 / 12 THR A 183
ILE A 217
ALA A 254
VAL A 290
PRO A 298
 None
 1.23A 3a51E-5jowA:
undetectable		 3a51E-5jowA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 7 VAL A  57
SER A  50
THR A 108
TRP A 133
 None
 1.16A 3arrA-5jowA:
undetectable		 3arrA-5jowA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		3 / 3 ARG A 326
ASP A 354
GLN A 393
 None
 0.67A 3lcvB-5jowA:
undetectable		 3lcvB-5jowA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		5 / 12 LEU A 256
VAL A 300
VAL A 215
TRP A 292
PRO A 289
 None
 1.27A 3mecA-5jowA:
undetectable		 3mecA-5jowA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 5 THR A 183
GLY A 229
PRO A 231
ASN A 233
 None
 1.24A 3u8qA-5jowA:
undetectable		 3u8qA-5jowA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 8 HIS A 412
ASP A 399
THR A 501
LEU A 392
 None
 1.22A 3wg7A-5jowA:
undetectable
3wg7C-5jowA:
undetectable
3wg7P-5jowA:
undetectable		 3wg7A-5jowA:
20.75
3wg7C-5jowA:
18.00
3wg7P-5jowA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		5 / 12 GLY A 304
VAL A  66
TYR A  23
ASN A  25
VAL A  27
 None
 1.34A 4ffwA-5jowA:
2.1		 4ffwA-5jowA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 5 PRO A  58
ASN A  48
ILE A  28
VAL A 267
 None
 1.38A 4hytA-5jowA:
undetectable		 4hytA-5jowA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 8 HIS A 412
ASP A 399
THR A 501
LEU A 392
 None
 1.21A 5b1aA-5jowA:
undetectable
5b1aC-5jowA:
undetectable
5b1aP-5jowA:
undetectable		 5b1aA-5jowA:
20.75
5b1aC-5jowA:
18.00
5b1aP-5jowA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 8 HIS A 412
ASP A 399
THR A 501
LEU A 392
 None
 1.21A 5b3sA-5jowA:
undetectable
5b3sC-5jowA:
undetectable
5b3sP-5jowA:
undetectable		 5b3sA-5jowA:
20.75
5b3sC-5jowA:
18.00
5b3sP-5jowA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 6 GLY A 252
SER A 205
VAL A 215
HIS A 192
 None
 0.83A 5ewuA-5jowA:
undetectable		 5ewuA-5jowA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 6 GLY A 252
SER A 205
VAL A 215
HIS A 192
 None
 0.84A 5ewuB-5jowA:
undetectable		 5ewuB-5jowA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 7 VAL A 119
PHE A 117
LEU A  75
THR A  76
 None
 0.93A 5m78A-5jowA:
undetectable		 5m78A-5jowA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 7 VAL A 132
MET A 152
ILE A 165
ASP A 166
 EDO  A 608 (-4.0A)
None
None
None
 0.90A 5yf9B-5jowA:
undetectable		 5yf9B-5jowA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 8 HIS A 412
ASP A 399
THR A 501
LEU A 392
 None
 1.22A 5zcoA-5jowA:
undetectable
5zcoC-5jowA:
undetectable
5zcoP-5jowA:
undetectable		 5zcoA-5jowA:
20.75
5zcoC-5jowA:
18.00
5zcoP-5jowA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		4 / 7 GLN A 342
GLY A 490
SER A  90
GLY A  89
 None
EDO  A 611 (-3.9A)
None
None
 0.98A 6ekzA-5jowA:
undetectable		 6ekzA-5jowA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		3 / 3 ASN A 343
PRO A  78
GLN A  80
 None
 0.80A 6jnhA-5jowA:
undetectable		 6jnhA-5jowA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A
(Bacteroides
ovatus) 		3 / 3 ASN A 343
PRO A  78
GLN A  80
 None
 0.82A 6jogA-5jowA:
undetectable		 6jogA-5jowA:
14.92