SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 4 SER A 609
SER A 697
LEU A 159
PHE A 155
 None
 1.25A 1r5lA-5jp0A:
undetectable		 1r5lA-5jp0A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 7 ILE A 111
ILE A 176
THR A 139
THR A 136
 None
 1.00A 1sbrB-5jp0A:
undetectable		 1sbrB-5jp0A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		3 / 3 TRP A 503
LEU A 539
LYS A 247
 None
 1.48A 1yajK-5jp0A:
undetectable		 1yajK-5jp0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		3 / 3 LYS A 781
ASP A 704
ASP A 756
 None
MG  A 802 (-2.5A)
None
 1.09A 2br4A-5jp0A:
undetectable		 2br4A-5jp0A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_F_SAMF501_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ASN A 538
TRP A 458
TRP A 454
TRP A 315
 None
 0.82A 2c2bC-5jp0A:
1.1
2c2bE-5jp0A:
1.1
2c2bF-5jp0A:
1.3		 2c2bC-5jp0A:
22.21
2c2bE-5jp0A:
22.21
2c2bF-5jp0A:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 7 GLU A 227
LYS A 165
ASN A 229
ALA A 168
 None
 1.41A 2ejgB-5jp0A:
undetectable		 2ejgB-5jp0A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 7 LEU A 429
PRO A 590
VAL A 565
MET A 588
 None
 1.35A 2hrcA-5jp0A:
undetectable		 2hrcA-5jp0A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 12 TRP A 394
LEU A 388
GLY A 226
VAL A 230
ALA A 231
 None
 1.27A 2kceA-5jp0A:
undetectable		 2kceA-5jp0A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 12 ARG A 549
LEU A 539
ARG A 570
GLY A 528
VAL A 584
 None
 1.23A 2zznA-5jp0A:
undetectable		 2zznA-5jp0A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 THR A 683
VAL A 684
LEU A 734
CYH A 761
 None
 1.16A 3b6rB-5jp0A:
undetectable		 3b6rB-5jp0A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 8 GLY A 460
TRP A 458
TYR A 497
ARG A 448
 None
 1.37A 3ccfA-5jp0A:
undetectable		 3ccfA-5jp0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 8 ILE A 133
ALA A 181
PHE A 217
ALA A 213
 None
 0.80A 3hrdA-5jp0A:
undetectable
3hrdB-5jp0A:
undetectable		 3hrdA-5jp0A:
20.03
3hrdB-5jp0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 PRO A 613
SER A 418
LEU A 699
SER A 697
 None
 1.47A 3ijxH-5jp0A:
undetectable		 3ijxH-5jp0A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 PRO A 613
SER A 418
LEU A 699
SER A 697
 None
 1.50A 3iluH-5jp0A:
undetectable		 3iluH-5jp0A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 9 ALA A 444
LEU A 477
VAL A 565
ILE A 431
LEU A 429
 None
 1.27A 3jw3B-5jp0A:
undetectable		 3jw3B-5jp0A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 10 LEU A 276
GLN A 218
GLU A 220
ASN A 223
ARG A 385
 None
 1.30A 3kp3A-5jp0A:
0.0
3kp3B-5jp0A:
0.0		 3kp3A-5jp0A:
12.03
3kp3B-5jp0A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 9 ALA A 275
LEU A 276
GLN A 218
ASN A 223
ARG A 385
 None
 1.22A 3kp6B-5jp0A:
undetectable		 3kp6B-5jp0A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 8 GLU A 197
TYR A 138
GLN A 459
ARG A 194
 None
None
None
BGC  A 801 (-2.9A)
 1.00A 3mjrD-5jp0A:
2.6		 3mjrD-5jp0A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 12 GLY A 187
GLU A 201
VAL A 205
PHE A 267
ASN A 198
 None
 1.16A 3qowA-5jp0A:
undetectable		 3qowA-5jp0A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 7 PHE A 354
ASN A 319
ALA A 334
LEU A 361
 None
 0.94A 3t3sC-5jp0A:
undetectable		 3t3sC-5jp0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 4 LEU A 186
GLY A 241
MET A 259
PHE A 267
 None
 1.49A 3vaqB-5jp0A:
4.7		 3vaqB-5jp0A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 PRO A 490
GLY A 441
LEU A 551
GLU A 509
 None
 0.90A 3zqtA-5jp0A:
undetectable		 3zqtA-5jp0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 GLU A 529
PRO A 442
TRP A 502
GLU A 505
 None
 1.40A 4a7tA-5jp0A:
3.6		 4a7tA-5jp0A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 GLU A 529
PRO A 442
TRP A 502
GLU A 505
 None
 1.39A 4a7tF-5jp0A:
3.8		 4a7tF-5jp0A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 GLU A 529
PRO A 442
TRP A 502
GLU A 505
 None
 1.35A 4a7uA-5jp0A:
3.6		 4a7uA-5jp0A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 GLY A 129
ILE A 127
VAL A 312
SER A  92
 None
 1.25A 4d33A-5jp0A:
undetectable		 4d33A-5jp0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 GLY A 129
ILE A 127
VAL A 312
SER A  92
 None
 1.24A 4d33B-5jp0A:
undetectable		 4d33B-5jp0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.19A 4w5oA-5jp0A:
3.4		 4w5oA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.20A 4w5qA-5jp0A:
3.9		 4w5qA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.19A 4w5rA-5jp0A:
3.9		 4w5rA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.19A 4w5tA-5jp0A:
3.9		 4w5tA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.15A 4z4cA-5jp0A:
3.4		 4z4cA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.18A 4z4dA-5jp0A:
3.4		 4z4dA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.18A 4z4eA-5jp0A:
2.0		 4z4eA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.17A 4z4fA-5jp0A:
3.4		 4z4fA-5jp0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ALA A 173
LYS A 104
THR A 136
THR A 139
 None
 1.14A 4z4iA-5jp0A:
2.3		 4z4iA-5jp0A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 9 ASP A 373
ALA A 377
VAL A 379
ARG A 381
LYS A  51
 None
 1.49A 4zbrA-5jp0A:
undetectable		 4zbrA-5jp0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 6 ASP A 258
LYS A 262
HIS A 263
ILE A 254
 None
 1.02A 5a06A-5jp0A:
2.5		 5a06A-5jp0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ASP A 258
LYS A 262
HIS A 263
ILE A 254
 None
 0.98A 5a06B-5jp0A:
2.1		 5a06B-5jp0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ASP A 258
LYS A 262
HIS A 263
ILE A 254
 None
 0.99A 5a06D-5jp0A:
undetectable		 5a06D-5jp0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 5 ASP A 258
LYS A 262
HIS A 263
ILE A 254
 None
 0.99A 5a06F-5jp0A:
2.4		 5a06F-5jp0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_DIFA601_1
(SERUM ALBUMIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 9 ASP A 373
ALA A 377
VAL A 379
ARG A 381
LYS A  51
 None
 1.35A 5dbyA-5jp0A:
undetectable		 5dbyA-5jp0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 9 VAL A 585
VAL A 563
TYR A 659
ILE A 431
LEU A 598
 None
 1.48A 5e4dA-5jp0A:
undetectable		 5e4dA-5jp0A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		5 / 12 ILE A 225
ARG A 385
LEU A 276
GLY A 216
GLY A 219
 None
 1.09A 5l6eA-5jp0A:
undetectable		 5l6eA-5jp0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		3 / 3 SER A 457
TYR A 456
TYR A 138
 None
 0.78A 5lakA-5jp0A:
undetectable
5lakI-5jp0A:
undetectable		 5lakA-5jp0A:
17.51
5lakI-5jp0A:
0.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		3 / 3 SER A 457
TYR A 456
TYR A 138
 None
 0.77A 5lakC-5jp0A:
undetectable
5lakJ-5jp0A:
undetectable		 5lakC-5jp0A:
17.51
5lakJ-5jp0A:
0.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		10 / 12 LEU A  94
ASP A 131
PHE A 180
ARG A 194
LYS A 235
HIS A 236
MET A 279
MET A 347
TRP A 454
GLU A 534
 None
BGC  A 801 (-3.0A)
BGC  A 801 ( 4.7A)
BGC  A 801 (-2.9A)
BGC  A 801 (-2.8A)
BGC  A 801 (-4.1A)
BGC  A 801 (-3.6A)
BGC  A 801 ( 3.7A)
None
BGC  A 801 (-2.6A)
 0.42A 5m6gA-5jp0A:
41.9		 5m6gA-5jp0A:
32.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		3 / 3 TYR A 593
ALA A 469
TYR A 470
 None
 0.67A 5uunB-5jp0A:
undetectable		 5uunB-5jp0A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 4 LEU A 542
ASP A 189
PRO A 190
ARG A 191
 None
 1.22A 6fgdA-5jp0A:
3.0		 6fgdA-5jp0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5jp0 BETA-GLUCOSIDASE
BOGH3B
(Bacteroides
ovatus) 		4 / 4 LEU A 623
ASP A 189
PRO A 190
ARG A 191
 None
 1.00A 6fgdA-5jp0A:
3.0		 6fgdA-5jp0A:
20.51