SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 5jp2 F-BAR DOMAIN ONLY
PROTEIN 1
(Danio
rerio) 		5 / 10 ARG A 937
THR A 914
ASP A 912
TYR A 999
PHE A 947
 None
 1.43A 4driB-5jp2A:
undetectable		 4driB-5jp2A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5jp2 EPIDERMAL GROWTH
FACTOR RECEPTOR
SUBSTRATE 15
F-BAR DOMAIN ONLY
PROTEIN 1
(Danio
rerio;
Homo
sapiens) 		5 / 12 TYR A 991
PHE E 636
GLY A 920
THR A 922
PHE E 625
 None
 1.43A 5v5zA-5jp2A:
undetectable		 5v5zA-5jp2A:
17.63