SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 6 TYR A 468
GLY A 467
GLY A 471
SER A 465
 None
 0.96A 1eswA-5jp3A:
undetectable		 1eswA-5jp3A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 LEU A 401
VAL A 423
LEU A 451
ALA A 445
VAL A 372
 None
 1.09A 1sn5B-5jp3A:
undetectable
1sn5D-5jp3A:
undetectable		 1sn5B-5jp3A:
16.67
1sn5D-5jp3A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 LEU A 451
ALA A 445
VAL A 372
LEU A 401
VAL A 423
 None
 1.09A 1sn5B-5jp3A:
undetectable
1sn5D-5jp3A:
undetectable		 1sn5B-5jp3A:
16.67
1sn5D-5jp3A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 10 ALA A 425
LEU A 451
ALA A 446
SER A 411
LEU A 412
 None
 1.07A 2bxgB-5jp3A:
undetectable		 2bxgB-5jp3A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 6 LEU A 413
SER A 411
ASP A 429
GLU A 458
 None
 1.19A 2j2pE-5jp3A:
undetectable
2j2pF-5jp3A:
undetectable		 2j2pE-5jp3A:
20.63
2j2pF-5jp3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 8 GLY A 477
ILE A 508
ALA A 482
GLU A 479
 None
 0.83A 2x0pA-5jp3A:
undetectable		 2x0pA-5jp3A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		3 / 3 ASP A 466
SER A 469
ARG A 505
 None
 0.90A 3loqA-5jp3A:
undetectable		 3loqA-5jp3A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		3 / 3 PRO A 503
LEU A 412
SER A 469
 None
 0.76A 5fsaB-5jp3A:
undetectable		 5fsaB-5jp3A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 LEU A 498
PHE A 400
PHE A 366
LEU A 412
VAL A 414
 None
 1.30A 6a93B-5jp3A:
undetectable		 6a93B-5jp3A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 11 THR A 456
GLU A 458
SER A 411
THR A 373
LEU A 375
 None
 1.47A 6efnA-5jp3A:
undetectable		 6efnA-5jp3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 5jp3 XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 6 ASP A 491
ASN A 360
LEU A 364
PHE A 400
 None
 1.00A 6ekuA-5jp3A:
undetectable		 6ekuA-5jp3A:
14.77