SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		5 / 10 ALA A  94
MET A  87
GLU A  91
GLU A 135
MET A 104
 None
 1.49A 1a29A-5jphA:
undetectable		 1a29A-5jphA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		3 / 3 ARG A  78
GLY A  79
SER A 116
 COA  A 202 (-3.6A)
COA  A 202 (-3.3A)
COA  A 202 ( 3.9A)
 0.59A 2xctB-5jphA:
undetectable		 2xctB-5jphA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 7 TYR A  47
THR A  55
ARG A  18
MET A  74
 None
CL  A 203 (-3.8A)
CL  A 203 (-4.0A)
None
 1.39A 3wipA-5jphA:
undetectable
3wipB-5jphA:
undetectable		 3wipA-5jphA:
19.56
3wipB-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 8 TYR A  47
THR A  55
ARG A  18
MET A  74
 None
CL  A 203 (-3.8A)
CL  A 203 (-4.0A)
None
 1.35A 3wipB-5jphA:
undetectable
3wipC-5jphA:
undetectable		 3wipB-5jphA:
19.56
3wipC-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 8 TYR A  47
THR A  55
ARG A  18
MET A  74
 None
CL  A 203 (-3.8A)
CL  A 203 (-4.0A)
None
 1.32A 3wipC-5jphA:
undetectable
3wipD-5jphA:
undetectable		 3wipC-5jphA:
19.56
3wipD-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 8 TYR A  47
THR A  55
ARG A  18
MET A  74
 None
CL  A 203 (-3.8A)
CL  A 203 (-4.0A)
None
 1.42A 3wipD-5jphA:
undetectable
3wipE-5jphA:
undetectable		 3wipD-5jphA:
19.56
3wipE-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 8 ARG A  18
MET A  74
TYR A  47
THR A  55
 CL  A 203 (-4.0A)
None
None
CL  A 203 (-3.8A)
 1.35A 3wipA-5jphA:
undetectable
3wipE-5jphA:
undetectable		 3wipA-5jphA:
19.56
3wipE-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		4 / 7 TYR A  47
THR A  55
ARG A  18
MET A  74
 None
CL  A 203 (-3.8A)
CL  A 203 (-4.0A)
None
 1.39A 3wipF-5jphA:
undetectable
3wipG-5jphA:
undetectable		 3wipF-5jphA:
19.56
3wipG-5jphA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 5jph ACETYLTRANSFERASE
SACOL1063
(Staphylococcus
aureus) 		5 / 9 LEU A  93
ARG A  57
THR A  55
LEU A  44
ILE A  45
 None
COA  A 201 (-3.8A)
CL  A 203 (-3.8A)
None
None
 1.23A 4ubsA-5jphA:
undetectable		 4ubsA-5jphA:
17.32