SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 189
TRP A 174
 None
 1.23A 1c4dC-5jpvA:
undetectable
1c4dD-5jpvA:
undetectable		 1c4dC-5jpvA:
12.82
1c4dD-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.28A 1c4dC-5jpvA:
undetectable
1c4dD-5jpvA:
undetectable		 1c4dC-5jpvA:
12.82
1c4dD-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 PHE A 257
ARG A 270
ASN A 208
 None
CL  A 305 (-4.4A)
None
 0.94A 1xzxX-5jpvA:
undetectable		 1xzxX-5jpvA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.17A 2xdcA-5jpvA:
undetectable
2xdcB-5jpvA:
undetectable		 2xdcA-5jpvA:
12.82
2xdcB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.43A 2xdcA-5jpvA:
undetectable
2xdcB-5jpvA:
undetectable		 2xdcA-5jpvA:
12.82
2xdcB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 174
VAL A 275
TRP A 210
 None
 1.43A 2xdcA-5jpvA:
undetectable
2xdcB-5jpvA:
undetectable		 2xdcA-5jpvA:
12.82
2xdcB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.19A 2xdcA-5jpvA:
undetectable
2xdcB-5jpvA:
undetectable		 2xdcA-5jpvA:
12.82
2xdcB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.27A 2xdcC-5jpvA:
undetectable
2xdcD-5jpvA:
undetectable		 2xdcC-5jpvA:
12.82
2xdcD-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.04A 2xdcC-5jpvA:
undetectable
2xdcD-5jpvA:
undetectable		 2xdcC-5jpvA:
12.82
2xdcD-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.07A 2xdcE-5jpvA:
undetectable
2xdcF-5jpvA:
undetectable		 2xdcE-5jpvA:
12.82
2xdcF-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.16A 2y5mA-5jpvA:
undetectable
2y5mB-5jpvA:
undetectable		 2y5mA-5jpvA:
12.82
2y5mB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.42A 2y5mA-5jpvA:
undetectable
2y5mB-5jpvA:
undetectable		 2y5mA-5jpvA:
12.82
2y5mB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.05A 2y5mE-5jpvA:
undetectable
2y5mF-5jpvA:
undetectable		 2y5mE-5jpvA:
12.82
2y5mF-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.16A 2y6nA-5jpvA:
undetectable
2y6nB-5jpvA:
undetectable		 2y6nA-5jpvA:
12.82
2y6nB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.43A 2y6nA-5jpvA:
undetectable
2y6nB-5jpvA:
undetectable		 2y6nA-5jpvA:
12.82
2y6nB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 174
VAL A 275
TRP A 210
 None
 1.42A 2y6nA-5jpvA:
undetectable
2y6nB-5jpvA:
undetectable		 2y6nA-5jpvA:
12.82
2y6nB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.17A 2y6nA-5jpvA:
undetectable
2y6nB-5jpvA:
undetectable		 2y6nA-5jpvA:
12.82
2y6nB-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.03A 2y6nC-5jpvA:
undetectable
2y6nD-5jpvA:
undetectable		 2y6nC-5jpvA:
12.82
2y6nD-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.03A 2y6nE-5jpvA:
undetectable
2y6nF-5jpvA:
undetectable		 2y6nE-5jpvA:
12.82
2y6nF-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.19A 3zq8A-5jpvA:
undetectable
3zq8B-5jpvA:
undetectable		 3zq8A-5jpvA:
12.82
3zq8B-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 189
TRP A 174
 None
 0.97A 3zq8C-5jpvA:
undetectable
3zq8D-5jpvA:
undetectable		 3zq8C-5jpvA:
12.82
3zq8D-5jpvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		5 / 12 GLU A 277
ASP A 224
THR A 226
THR A 192
GLU A 196
 CA  A 304 (-2.3A)
None
None
CA  A 304 ( 4.8A)
CA  A 304 (-2.4A)
 1.22A 4njkA-5jpvA:
undetectable		 4njkA-5jpvA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5jpv ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		5 / 12 GLU A 277
ASP A 224
THR A 226
THR A 192
GLU A 196
 CA  A 304 (-2.3A)
None
None
CA  A 304 ( 4.8A)
CA  A 304 (-2.4A)
 1.20A 4njkB-5jpvA:
undetectable		 4njkB-5jpvA:
20.94