SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		3 / 3 GLU A 518
HIS A 526
ASP A 497
 None
 0.71A 1i9gA-5jpzA:
undetectable		 1i9gA-5jpzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 4 ALA A 327
ARG A 328
GLN A 330
GLU A 320
 None
 1.28A 1lqtB-5jpzA:
undetectable		 1lqtB-5jpzA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 4 ALA A 327
ARG A 328
GLN A 330
GLU A 320
 None
 1.30A 1lquB-5jpzA:
undetectable		 1lquB-5jpzA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 11 PHE A 210
ARG A 212
ALA A 213
ALA A 176
GLU A 174
 None
 0.95A 2bxeB-5jpzA:
4.3		 2bxeB-5jpzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 11 PHE A 333
ARG A 335
ALA A 336
ALA A 301
GLU A 299
 None
 0.98A 2bxeB-5jpzA:
4.3		 2bxeB-5jpzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 GLN A 330
TYR A 353
ARG A 370
HIS A 368
 None
 1.42A 2vxaA-5jpzA:
undetectable
2vxaB-5jpzA:
undetectable
2vxaK-5jpzA:
undetectable		 2vxaA-5jpzA:
9.70
2vxaB-5jpzA:
9.70
2vxaK-5jpzA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 GLN A 330
TYR A 353
ARG A 370
HIS A 368
 None
 1.45A 2vxaD-5jpzA:
undetectable
2vxaE-5jpzA:
undetectable
2vxaL-5jpzA:
undetectable		 2vxaD-5jpzA:
9.70
2vxaE-5jpzA:
9.70
2vxaL-5jpzA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 TYR A 285
ASP A 261
LEU A 289
LYS A 296
 None
 1.00A 4f8hA-5jpzA:
3.4
4f8hB-5jpzA:
2.9		 4f8hA-5jpzA:
21.06
4f8hB-5jpzA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 TYR A 285
ASP A 261
LEU A 289
LYS A 296
 None
 1.02A 4f8hB-5jpzA:
2.9
4f8hC-5jpzA:
3.1		 4f8hB-5jpzA:
21.06
4f8hC-5jpzA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 TYR A 285
ASP A 261
LEU A 289
LYS A 296
 None
 1.01A 4f8hC-5jpzA:
3.1
4f8hD-5jpzA:
3.6		 4f8hC-5jpzA:
21.06
4f8hD-5jpzA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 TYR A 285
ASP A 261
LEU A 289
LYS A 296
 None
 1.00A 4f8hD-5jpzA:
3.6
4f8hE-5jpzA:
3.6		 4f8hD-5jpzA:
21.06
4f8hE-5jpzA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		4 / 8 LEU A 289
LYS A 296
TYR A 285
ASP A 261
 None
 1.00A 4f8hA-5jpzA:
2.9
4f8hE-5jpzA:
3.6		 4f8hA-5jpzA:
21.06
4f8hE-5jpzA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ARF_A_SAMA1002_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		5 / 12 ARG A 132
ALA A 160
TYR A 192
TYR A 170
PHE A 173
 None
 1.43A 5arfA-5jpzA:
4.6		 5arfA-5jpzA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3
(Homo
sapiens) 		3 / 3 GLU A 518
HIS A 526
ASP A 497
 None
 0.66A 5c0oG-5jpzA:
undetectable		 5c0oG-5jpzA:
20.12