SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5jqc LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 6 LEU A 284
VAL A 269
MET A 321
PHE A 311
 None
 1.05A 3soaA-5jqcA:
undetectable		 3soaA-5jqcA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5jqc LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 0.99A 6e43A-5jqcA:
undetectable		 6e43A-5jqcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5jqc LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 0.96A 6e43B-5jqcA:
undetectable		 6e43B-5jqcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5jqc LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 1.00A 6e43C-5jqcA:
undetectable		 6e43C-5jqcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5jqc LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 0.88A 6e43D-5jqcA:
undetectable		 6e43D-5jqcA:
21.18