SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  94
GLU A 255
THR A 101
 None
 0.97A 2y7hB-5jqmA:
undetectable		 2y7hB-5jqmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  40
ILE A  79
LEU A  98
ASP A 250
 None
 0.76A 4dtaB-5jqmA:
undetectable		 4dtaB-5jqmA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		4 / 5 GLY A  48
THR A  90
VAL A  83
ASP A  45
 None
 1.14A 4eohA-5jqmA:
undetectable		 4eohA-5jqmA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		5 / 9 SER A 145
PHE A 149
SER A 130
LEU A   3
VAL A   2
 None
 1.45A 4z69A-5jqmA:
undetectable		 4z69A-5jqmA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  84
VAL A  44
GLY A  48
PHE A 215
 None
 0.99A 5d4nA-5jqmA:
1.0
5d4nC-5jqmA:
1.1		 5d4nA-5jqmA:
17.88
5d4nC-5jqmA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 200
LYS A 187
SER A 189
 None
 1.46A 5odiA-5jqmA:
undetectable		 5odiA-5jqmA:
17.68