SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7R_A_NCTA440_1 (CYTOCHROME P450-CAM)	5jqp	GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	PHE B 42 VAL B 28 ASP B 69 ILE B 57	None None CA B1001 (-3.3A) None	0.87A	1p7rA-5jqpB: undetectable	1p7rA-5jqpB: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T88_A_CAMA1422_0 (CYTOCHROME P450-CAM)	5jqp	GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	PHE B 42 VAL B 28 GLY B 27 ASP B 69	None None None CA B1001 (-3.3A)	1.00A	1t88A-5jqpB: undetectable	1t88A-5jqpB: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1498_1 (CYTOCHROME P450 3A4)	5jqp	GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	SER B 49 LEU B 88 ILE B 50 THR B 101 LEU B 92	None	1.34A	2v0mD-5jqpB: undetectable	2v0mD-5jqpB: 14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DRJ_A_RAPA201_2 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 SERINE/THREONINE-PRO TEIN KINASE MTOR)	5jqp	GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	SER B 68 THR B 41 TYR B 35 PHE B 32	None	1.07A	4drjB-5jqpB: undetectable	4drjB-5jqpB: 19.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P7R_A_NCTA440_1","CYTOCHROME P450-CAM","5jqp","GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN","Chaetomium thermophilum",4,"PHE B  42;VAL B  28;ASP B  69;ILE B  57","None;None; CA B1001 (-3.3A);None","0.87A","1p7rA-5jqpB:undetectable","1p7rA-5jqpB:17.37"],["1T88_A_CAMA1422_0","CYTOCHROME P450-CAM","5jqp","GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN","Chaetomium thermophilum",4,"PHE B  42;VAL B  28;GLY B  27;ASP B  69","None;None;None; CA B1001 (-3.3A)","1.00A","1t88A-5jqpB:undetectable","1t88A-5jqpB:17.37"],["2V0M_D_KLND1498_1","CYTOCHROME P450 3A4","5jqp","GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN","Chaetomium thermophilum",5,"SER B  49;LEU B  88;ILE B  50;THR B 101;LEU B  92","None","1.34A","2v0mD-5jqpB:undetectable","2v0mD-5jqpB:14.02"],["4DRJ_A_RAPA201_2","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4;SERINE\/THREONINE-PROTEIN KINASE MTOR","5jqp","GLUCOSIDASE 2 SUBUNIT BETA-LIKE PROTEIN","Chaetomium thermophilum",4,"SER B  68;THR B  41;TYR B  35;PHE B  32","None","1.07A","4drjB-5jqpB:undetectable","4drjB-5jqpB:19.16"]]